Gastro

Question 1

Alagille Syndrome 1. Aetiology 2. Pathology 3. Presentation 4. Associations 5. Cardiac anomaly? 6. Mgmt

Answer 1

1. JAG1 mutation 2. Reduced interlobular bile ducts 3. Triangle head, posterior embryotoxon = thick border around iris. Jaundice. 4.Butterfly vertebrae. Tubulointerstitial nephropathy. Short. Pancreatic Insufficiency. 5. Peripheral pulmonary stenosis. 6. Liver transplant

Question 2

What Immunoglobulin is best secreted in breast milk?

Answer 2

IgA

Question 3

What Immunoglobulin is transferred accross the placenta?

Answer 3

IgG

Question 4

Bowel Obstruction Complication in CF

Treatment

Answer 4

DIOS

Lots of Movicol

PO Gastrograffin (or Rectal is ++++Vomiting)

Oral N-Acetyl Cystine

Klean-Prep

Rarely surgery

Question 5

Haemachromatosis type of inheritance?

Answer 5

AR!

Question 6

Gene for Wilsons and Treatment

Answer 6

ATP7B on Ch13

Penicillamine, Trientine, Zinc