Immunology Flashcards

1
Q

Hematopoieses

A

Body’s ability to regulate, produce, and develop blood cells

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2
Q

Self recognition

A

The body’s ability to know self from non self

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3
Q

Homeostasis

A

Body’s ability to maintain a balance of blood cell supply

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4
Q

Immune surveillance

A

Implies the recognition and destruction of malignant or altered cells

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5
Q

Blood cell development begins with what cell

A

The pluripotent stem cell

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6
Q

What does the pluripotent stem cell divide into

A

Undifferentiated stem cells that are committed to either being a lymphoid or a myeloid

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7
Q

The myeloid cell line produces what?

A

Monocytes and polymorphonuclear leukocytes

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8
Q

What is developed from a lymphoid cell line?

A

B lymphocytes and T lymphocytes

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9
Q

This functions as antigen-presenting cells for naive T cells

A

Dendritic cells

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10
Q

NK cell function

A

To identify and destroy virus infected cells and certain tumor cells

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11
Q

Auxiliary cells do what?

A

They are mediators or inflammation that play a pivotal role in attracting leukocytes towards a site of infection

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12
Q

Primary lymphoid organs do what?

A

Allow for the maturation of lymphocytes including antigen receptors

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13
Q

What is agglutination?

A

The result of complement products that make the outer coatings of invading cells sticky. In the process agglutination can change the structures of some viruses, making them non virulent

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14
Q

What happens in first stage of the inflammatory response?

A

The release of vasoactive amines from basophils, eosinophils, and mast cells

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15
Q

What is humoral immunity?

A

The first type of acquired immunity that is associated with B cell activity

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16
Q

Describe a monocytes/macrophage

A

Distributed throughout the tissue and are capable of phagocytosis

17
Q

What does the B cell produce

A

Antibodies specific to antigen

18
Q

Mast cell or basophils releases what?

A

Histamine and chemotactic factors

19
Q

What does a NK cell have the unique ability to do?

A

Release a substance that triggers lysis of the invading cell

20
Q

What type of phagocyte is particularly effective against large extra cellular parasites?

A

Eosinophil polymorphs

21
Q

What cytokines limits the spread of certain viral infections, is produced early in response to infection, and offers the first line of viral resistance?

A

Interferons

22
Q

What is innate immunity?

A

It is a cascade of mechanisms that occur before onset of infection

23
Q

What is passive immunization?

A

The transfer of antibodies from an immunized individual to a nonimmunized individual (pregnancy)

24
Q

How do tumor cells evade immune systems?

A

The loss of the ability to express antigens on tumor cells allows for the rapid and uncontrolled growth of tumors because immune cell response is altered