Immunology

Question 0

T Helper 1 cells job

Answer 0

Release of proinflammatory cytokines (IL-2, INF g)

Question 1

What is released by T Helper cells? CD4

Answer 1

IL-4…B cell to plasma cells

IL-2….mature cytotoxic T

Question 2

T Helper 2 cells job

Answer 2

Release anti inflammatory cells ( IL-4-inhibits macrophages

Question 3

Cytotoxic T cells CD8 job

Answer 3

Attack non self antigens attached to MHC 1 receptors ( viral gene prod)

Question 4

MHC Class 1 (A,B,C) job

Answer 4

CD8 activation
Target for cytotoxic T
Single chain with 5 domains

Question 5

MHC Class II (DR, DP, DQ)….. (2letters) job

Answer 5

CD4 activation
On B cells
Activate for helper T
2 chains with 4 domains

Question 6

MHC I is associated with what CD?

Answer 6

CD8- cytotoxic Ts

Question 7

MHC II is associated with what CD?

Answer 7

CD4- helper T

Question 8

Initial antibody made after exposure to antigen

Answer 8

IgM - largest antibody

Question 9

Most abundant antibody in the body

Answer 9

IgG- can cross placenta and provide newborn protection

Question 10

Type I hypersensitivity

Answer 10

Allergic rxn…. IgE mediated

Question 11

Type II hypersensitivity rxn

Answer 11

IgG or IgM with antigen

ABO incompat, Rh incompat, graves, ITP

Question 12

Type III hypersensitivity rxn

Answer 12

Immune complex desposition

Rheumatoid, sle, serum sickness

Question 13

Type IV hypersensitivity rxn

Answer 13

Delayed

TB test, contact dermatitis

Question 14

Tx for non tetanus prone wounds

Answer 14

Tetanus toxoid only if pt received <3 doses or unknown

Question 15

Tx for tetanus prone wounds

Answer 15

> 6 hrs- tetanus toxoid

Question 16

When to give tetanus immune globulin

Answer 16

Tetanus prone wound who have not been immunized or unknown