Anesthesia Flashcards

0
Q

Small MAC equals…

A

More lipid soluble -> more potent, slower induction

Ex: Nitrous oxide-> low potency, fast induction

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1
Q

What does MAC stand for and what does it mean?

A

Minimum alveolar concentration

Smallest concentration of inhaled agent at which 50% of pts will not move with the first incision

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2
Q

No Nitrous oxide with…

A

Anywhere with confined spaces- pneumo, SBO

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3
Q

Nitrous oxide

A

Fast onset
Low potency
LEAST myocardial depression

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4
Q

Inhaled agent with highest degree of cardiac depression

A

Halothane- good for kids

Halothane hepatitis- fever, increased eos, jaundice, inc LFT’s

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5
Q

Sevoflurane

A

Less myocardial depression
Fast
Less laryngospasm
$$$

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6
Q

Induction agents

A

Barbiturate- sodium thiopental
Propofol
Ketamine
Etomidate

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7
Q

Do not use propofol in pts with what allergy?

A

Egg

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8
Q

What does ketamine cause?

A

Dissociation of thalmic/limbic system
Hallucinations
Catecholamine release- inc carbon monoxide, tachy

NO in pts with head injury

Good for kids

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9
Q

Etomidate

A

Fast
Fewer hemodynamic changes

Cont infusions can cause adrenocortico suppression

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10
Q

Paralytics

A
Succinylcholine- de polarizing
Cis-atracurium- Hoffman deg- ok in liver and renal failure
Mivacurium
Rocuronium
Pancuronium - tachy
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11
Q

De polarizing agent

A

Succinylcholine
Fast, short acting
Causes fasciculations at first- flaccid paralysis

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12
Q

Succinylcholine contraindicated with…

A

Hyperkalemia- depolarization causes release of K
No in burn pts, neurologic injury, neuromuscular disorders, spinal cord injury, massive trauma, renal failure, head injury

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13
Q

Complication of succinylcholine

A

Malignant hyperthermia
Ca released from SR causes muscle excitation/contraction syndrome

1st sign- inc end tidal CO2
Tachy, rigid, acidosis, inc K

Atypical psuedocholinesterases- prolonged paralysis- Asians

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14
Q

Treatment of malignant hyperthermia

A

Dantrolene 10mg/kg
Inhibits Ca release
Cooling blanket, HCO3, glucose

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15
Q

What nondepolarizing agent can be used in liver or renal failure?

A

Cis- atracurium

Hoffman degradation
Histamine release

16
Q

What is the side effect of pancuronium?

A

Tachycardia

Nondepolarizing mm relaxant/paralyzer

17
Q

Reversing drugs for nondepolarizing agents

A

Neostigmine - blocks acetylcholinesterase- more Ach

Edrophonium-blocks

Atropine & glycopyrrolate - have to be given with neo or Edro to counteract Ach overdose

18
Q

Max dose of 1%lido

A

5mg/kg

19
Q

Max dose of lido + epi

A

7mg/kg

20
Q

Max dose of bupivicaine

A

3mg/kg

21
Q

Amides…

A

All have i in first part of name

Rare allergic rxns

22
Q

Esters…..

A

Increased allergic rxns due to PABA analogue

23
Q

Demerol complications

A

Tremors
Fasciculations
Convulsions

In renal failure can cause seizures

24
Q

Overdose of benzodiazepine is treated with

A

Flumazenil ( contra in pts with inc ICP)

25
Q

Tx for acute hypotension and Brady in epidural anesthesia

A

Stop epidural, fluids, phenylephrine, atropine

26
Q

Spinal anesthesia injected into what space?

A

Subarachnoid space

No with hypertrophic cardio, cyanotic heart dz

27
Q

Treatment spinal headache

A

Fluids caffeine
>24hrs- blood patch- place 10-20ml blood into epidural space

Due to CSF leaking - brain sags into cranial vault- traction on pain fibers

28
Q

Complication of neuroaxial anesthesia

A

Epidural hematoma

29
Q

ASA classifications

A
I- healthy
II- mild dz without limitation
III- severe dz
IV- constant threat to life
V-moribund- not expected to survive OR
VI- donor
30
Q

Placement of endotracheal tube

A

2cm above carina