Anesthesia Flashcards
Small MAC equals…
More lipid soluble -> more potent, slower induction
Ex: Nitrous oxide-> low potency, fast induction
What does MAC stand for and what does it mean?
Minimum alveolar concentration
Smallest concentration of inhaled agent at which 50% of pts will not move with the first incision
No Nitrous oxide with…
Anywhere with confined spaces- pneumo, SBO
Nitrous oxide
Fast onset
Low potency
LEAST myocardial depression
Inhaled agent with highest degree of cardiac depression
Halothane- good for kids
Halothane hepatitis- fever, increased eos, jaundice, inc LFT’s
Sevoflurane
Less myocardial depression
Fast
Less laryngospasm
$$$
Induction agents
Barbiturate- sodium thiopental
Propofol
Ketamine
Etomidate
Do not use propofol in pts with what allergy?
Egg
What does ketamine cause?
Dissociation of thalmic/limbic system
Hallucinations
Catecholamine release- inc carbon monoxide, tachy
NO in pts with head injury
Good for kids
Etomidate
Fast
Fewer hemodynamic changes
Cont infusions can cause adrenocortico suppression
Paralytics
Succinylcholine- de polarizing Cis-atracurium- Hoffman deg- ok in liver and renal failure Mivacurium Rocuronium Pancuronium - tachy
De polarizing agent
Succinylcholine
Fast, short acting
Causes fasciculations at first- flaccid paralysis
Succinylcholine contraindicated with…
Hyperkalemia- depolarization causes release of K
No in burn pts, neurologic injury, neuromuscular disorders, spinal cord injury, massive trauma, renal failure, head injury
Complication of succinylcholine
Malignant hyperthermia
Ca released from SR causes muscle excitation/contraction syndrome
1st sign- inc end tidal CO2
Tachy, rigid, acidosis, inc K
Atypical psuedocholinesterases- prolonged paralysis- Asians
Treatment of malignant hyperthermia
Dantrolene 10mg/kg
Inhibits Ca release
Cooling blanket, HCO3, glucose