Immunology Flashcards
1
Q
Azathioprine
A
MOA: Purine antimetabolite, impairs lymphocyte proliferation
Interacts with allopurinol and febuxostat 0> increased risk of bone marrow toxicity
Side Effects: Myelosuppression, mouth ulcers, oesophagitis, Hepatitis, photosensitivity, hypersensitivity syndrome (SJS/TEN, Pneumonitis), Interstitial Nephritis
2
Q
Cyclophosphamide
A
MOA: Alkylating agent -> cytotoxic to lymphocytes by interfering with DNA cross linking
