Haematology Flashcards

1
Q

Pathophysiology of Anaemia of Chronic Disease

A

Reduced absorption of iron from GI Tract
Reduced EPO production
Sequestration of iron in macrophages
Increased Hepcidin

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2
Q

Causes of MAHA

A

DIC
HUS
TTP
Valve Related Haemolysis

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3
Q

What condition is the EMA Test for?

A

Hereditary Spherocytosis

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4
Q

What is the pathology in Hereditary Spherocytosis?

A

Mutations involving erythrocyte membrane proteins:
- Ankyrin
- Spectrin
- Band 3
Results in sequestration of spherocytes

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5
Q
A
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