Haematology Flashcards
1
Q
Pathophysiology of Anaemia of Chronic Disease
A
Reduced absorption of iron from GI Tract
Reduced EPO production
Sequestration of iron in macrophages
Increased Hepcidin
2
Q
Causes of MAHA
A
DIC
HUS
TTP
Valve Related Haemolysis
3
Q
What condition is the EMA Test for?
A
Hereditary Spherocytosis
4
Q
What is the pathology in Hereditary Spherocytosis?
A
Mutations involving erythrocyte membrane proteins:
- Ankyrin
- Spectrin
- Band 3
Results in sequestration of spherocytes
5
Q
A