Immunology

Question 1

Antigen Presenting Cells

Answer 1

Macrophages, Monocyte, Neutrophiles, Eosinophils, Basophils

Question 2

Eosinophils

Answer 2

Parasitic and allergic reactions

Question 3

Which APC is not phagocytic

Answer 3

Basophils

Question 4

Which APC is most common

Answer 4

Neutrophils

Question 5

Laugerhan

Answer 5

Macrophages in the skin

Question 6

T-cells

Answer 6

Specific lymphocytes. Divide into Helper (CD4) and T cytotoxic (CD8)

Question 7

B-cells

Answer 7

Specific lymphocytes. Make plasma cells which make AB.

Question 8

Natural Killer Cells

Answer 8

Non specific lymphocytes. Do not need APC.

Question 9

FAB portion of AB

Answer 9

bind antigens. Has a light and heavy chain

Question 10

FC potion of AB

Answer 10

compliment and constant portion

Question 11

Kupffer cells

Answer 11

APC in the liver

Question 12

Non specific Immunity

Answer 12

Natural killer, interferon, Compliment (IgG, IGA, IGM)

Question 13

What is the first thing to arrive with infection

Answer 13

Neutrophils (PMN)s.

Question 14

What makes pus (suppuration)

Answer 14

PMNs

Question 15

Which cells are PMNs

Answer 15

BEN. Basophils, neutrophils, eosinophils.

Question 16

What do PMNs release

Answer 16

Granulocytes full of proteolytic enzymes that break down antigens

Question 17

Interferon

Answer 17

Nonspecific and increased in viral infections

Question 18

Beta interferon

Answer 18

Used for MS

Question 19

Alpha Interferon

Answer 19

Used for Hepatitis C.

Question 20

What does complement pathway do

Answer 20

CODD. Chemotaxis of neutrophils and macrophages, Opsonization, Degranulation of mast cells, direct lysis of bacteria

Question 21

Classic Complement pathway

Answer 21

GM motors. IgG, IGM.

Question 22

Alternative complment pathway

Answer 22

IgA and bacterial endotoxins.

Question 23

In laments terms what is Specific immunity

Answer 23

T cells telling B cells to make specific AB

Question 24

Where are B and T lymphocytes made

Answer 24

Bone

Question 25

Where do T lymphocytes mature

Answer 25

thymus

Question 26

where do B lymphocytes mature

Answer 26

Bone marrow

Question 27

Steps of Specific immunity

Answer 27

APC, Antigen must match, Receptors must match

Question 28

T helper cell has what receptor and who do they match

Answer 28

CD4 and match MHC II

Question 29

T killer cells have what receptor and who do they match

Answer 29

CD8 and match MHC I

Question 30

What happens after Macrophage matches with T-helper cell?

Answer 30

Sends IL-1 to T helper cell. Then T-helper cell sends IL-2 to B cells to create Ab

Question 31

When do Killer T cells work

Answer 31

Viral infections

Question 32

What does restates do?

Answer 32

Stops new release of IL2

Question 33

Type 4 hypersensitivty

Answer 33

Mediated by T killer cells.

Question 34

Haptin

Answer 34

Happens with Type 4 and T killer. SO small must bind protein for a reaction.

Question 35

Who do we order ANA for?

Answer 35

Lupus or other autoimmune.