IMMUNOLOGY

Question 1

Antigens shared by genetically identical twins are characterized as____

Answer 1

SYNGENEIC

Question 2

antibodies are formed AFTER EXPOSURE to environmental agents

Answer 2

NATURALLY OCCURING

Question 3

IMMUNOGENICITY is influenced by _____,____,____,_____,_____,&_________

Answer 3

foreigness
molecular size
chemical complexity
route, dosage & timing

Question 4

ability of the antigen to induce antibody formation

Answer 4

Immunogenicity

Question 5

tests performed in Paternity testing

Answer 5

HLA typing and DNA testing

Question 6

Purified ____ cell is used for HLA class II typing

Answer 6

B cell

Question 7

Purified ____ cell is used for HLA class I typing

Answer 7

T cell

Question 8

anticoagulant used for HLA phenotyping, DNA & paternity testing

Answer 8

ACD

Question 9

MHC Class with chain structure of alpha chain + B2-microglobulin

Answer 9

Class I

Question 10

Cell distribution of MHC Class I

Answer 10

all nucleated cells

Question 11

Cell distribution of MHC Class II

Answer 11

B cells, antigen presenting cells (APCs)

Question 12

mitogen that activates B cells

Answer 12

Lipopolysaccharide

Question 13

mitogen that activates T cells

Answer 13

Phytohemagglutinin, Concanavalin A

Question 14

mitogen that activates B and T cells

Answer 14

Pokeweed mitogen

Question 15

substance added to vaccine to enhance immune response

Answer 15

ADJUVANTS

Question 16

IL-8 function

Answer 16

Inflammatory

Question 17

induces fever, mediator of acute phase response

Answer 17

IL-1

Question 18

Cytokines produced by NK cells and Activated T cells

Answer 18

Interferon-gamma

Question 19

functions of cytokines

Answer 19

Immunoregulation

Question 20

a test for chemotaxis

Answer 20

Boyden Chamber

Question 21

STIMULATES leukocyte movement and attraction

Answer 21

Chemokines

Question 22

CYTOKINES

Answer 22

1) chemokines
2) interferons
3) Interleukins
4) tumor necrosis factor
5) lymphotoxin
6) TGF

Question 23

How are phagocytes able to interact with microorganisms DIRECTLY?

Answer 23

via PPRR or Primitive Pattern Recognition Receptors

Question 24

passage of blood or any of its formed elements through an intact blood vessel

Answer 24

Diapedesis

Question 25

Steps of Phagocytosis

Answer 25

TURGEON: 1) Chemotaxis, 2) Adherence, 3) Engulfment, 4) Phagosome formation, 5) Fusion, 6) Digestion & destruction 1) inititaion, 2) Chemotaxis, 3) Engulfment, 4) Digestion

Question 26

what cell is treated with MYTOMYCIN C in mixed lymphocyte culture

Answer 26

Donor lymphocytes

Question 27

how are monoclonal antibodies produced?

Answer 27

in vivo and in vitro

Question 28

hybridomas are formed from

Answer 28

B cell / Plasma cell

Question 29

major site of antibody production

Answer 29

Spleen

Question 30

dendritic cell in epidermis

Answer 30

Langerhan cell

Question 31

most potent antigen presenting cell

Answer 31

dendritic cell

Question 32

macrophage found in the liver

Answer 32

Kupffer cell

Question 33

resembles mast cell

Answer 33

basophil

Question 34

protein released by eosinophils that are toxic to parasites

Answer 34

Major Basic Protein, | Eosinophilic Cationic Protein

Question 35

Cells to be considered as homeostatic regulator of inflammation

Answer 35

Eosinophils