HEMATOLOGY Flashcards

1
Q

GRADED AS POSITIVE only

A

Sickle cells
Basophilic stippling
Pappenheimer bodies
Howell-Jolly bodies

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2
Q

2+ Spherocytes

A

6-10/field

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3
Q

> 10/field acanthocytes

A

3+

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4
Q

ovalocytes 3-10/field

A

1+

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5
Q

codocyte >20/field

A

3+

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6
Q

15 stomatocytes/field

A

2+

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7
Q

normal platelet estimate

A

200,000 - 400,000/uL

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8
Q

MODERATE increase in platelet estimate

A

600,000-800,000/uL

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9
Q

LOW NORMAL in platelet estimate

A

150,000-199,000/uL

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10
Q

Anulocyte is graded as

A

4+

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11
Q

has a thin rim of hemoglobin

A

Anulocyte (4+)

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12
Q

endpoint of a fibrometer

A

clot formation

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13
Q

25-50% macrocytosis graded as

A

2+ to 3+

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14
Q

3% polychromasia graded as

A

1+

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15
Q

Rouleaux graded as “MARKED”

Hubbard

A

5 or more RBC chains are found per thin microscopic field

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16
Q

aggregates 5-10 RBCs graded as

A

2+

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17
Q

hypochromia grading of >2/3

A

2+ to 3+

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18
Q

automated coagulation instrument

A
MDA
STA-R
ACL
AMAX
BCR
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19
Q

Semi -automated coagulation instrument

A

Fibrometer
KC4 Delta
STart4

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20
Q

When 2 cells pass through an orifice simultaneously & counted as 1 cell

A

COINCIDENCE

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21
Q

OHM’S LAW formula

A

V= I x R

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22
Q

Effect of cold agglutinins in RBC parameters

A

decrease RBC count, HCT

increase MCV, MCHC

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23
Q

increase RBC count, HCT

decrease MCV, MCHC

A

autoagglutination

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24
Q

most common problem in cell counting, causing increase in current

A

Aperture plugs

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25
Q

an error caused by nature of specimen that makes accurate RBC & platelet count impossible

A

increased number of schistocytes

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26
Q

(+) or (-) error

A

improper setting of aperture current or threshold

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27
Q

Values derived from RBC histogram

A

RDW & MCV

28
Q

Values derived from platelet histogram

A

MPV & PDW

29
Q

PRINTED on elec. impedance written report

A

Scattergram
histogram
flagging

30
Q

side angle or 90’ light scatter measures

A

Cytoplasmic granularity

31
Q

MPV should be measured at what time period

A

1-3 hours after collection

32
Q

forward light scatter measures

A

cell size

33
Q

components of flowcytometer

A

computer
Optics
Fluidics
Electronics

34
Q

principle of Technicon analyzer

A

optical light scattering

35
Q

principle of Coulter counter and Sysmex counter

A

Electrical impedance

36
Q

Directly counted by the electrical impedance instrument

A
RBC
WBC
Platelet
Hgb
reticulocytes
37
Q

automation principle that uses 2 electrodes to determine cell size

A

Electrical impedance

38
Q

dilution of RBC count using automated counting instrument

A

1:50,000

39
Q

in WBC CATEGORIES ON COULTER COUNTER, small cells refer to

A

Lymphocytes

40
Q

in WBC CATEGORIES ON COULTER COUNTER, medium cells refer to

A

Mononuclear cells

41
Q

in WBC CATEGORIES ON COULTER COUNTER, large cells refer to

A

Granulocytes

42
Q

effect of microcytosis on platelet count using automated counters

A

Spurious increase

43
Q

size of microcytic RBCs

A

<6um

44
Q

Screening tests for ANEMIA ASSOCIATED WITH CHRONIC BLEEDING; BM RESPONSE

A

Hgb
Hct
reticulocyte count

45
Q

Screening tests for thrombocytopenia

A

Platelet count

46
Q

Screening tests for deficiencies of factors II, V, VII or X (CT prolonged)

A

Prothrombin Time

47
Q

Screening tests for deficiencies of all factors except VII & XIII (CT prolonged)

A

Partial Thromboplastin Time

48
Q

Screening tests for Hypofibrinogenemia and dysfibrinogenemia

A

Thrombin time or fibrinogen assay

49
Q

a screening procedure for the measurement of fibrinolytic activity

A

Euglobin clot lysis time

50
Q

the CLOSER the ISI to 1 the ______ the reagent is

A

MORE SENSITIVE

51
Q

the HIGHER the ISI to 1 the ____ the reagent is

A

LESS SENSITIVE

52
Q

Angle 2 of RBC Analysis in Technicon

A

High-angle forward scatter, 5-15’

53
Q

target INR for pulmonary embolism

A

2.5

54
Q

INR for preventing DEEP VEIN THROMBOSIS

A

2 to 3

55
Q

specimens for PT and APTT must be centrifuged within ___

A

1 hour (60 minutes)

56
Q

specimen for APTT must be TESTED within ____

A

4 hours

57
Q

specimen for PT must be TESTED within ____

A

24 hours

58
Q

centrifuge blood for

A

15 mins @ 1500 g

59
Q

PT reagent

A

Thromboplastin-Calcium Chloride (0.2 mL or 200 uL)

60
Q

APTT reagent

A

activator + phospholipid

61
Q

volume of plasma for PT testing

A

0.1 mL (100 uL)

62
Q

volume of plasma for APTT testing

A
  1. 2 mL (200uL) - Brown

0. 1 mL (100 uL) - Steininger

63
Q

VISUAL detection of fibrin clot formation

A

Tilt-tube method

64
Q

in DIC, D-dimer test will be positive after how many hours

A

4 hours

65
Q

Bethesda assay

A

test for quantitating factor VIII inhibitor