Immunological memory Flashcards
1
Q
AB memory vs T cell
A
AB has no real decline
T cell will show some
2
Q
B cell secondary response
A
IgA, IgG, high affinity, high somatic hypermutation
3
Q
As time increases, which 2 thingsa about AB change
A
Affinity increases and more IgG
4
Q
When does T cell response peak
A
About a week and then declines
5
Q
What 2 things are increased in memory cells and why>
A
Bcl2 - pro survival
IL-7 receptor (CD127)
6
Q
Memory cells can become
A
Central or effector memory cells
7
Q
Mucosal immunity - intestines
A
More microbiota in large Peyers patches Paneth cells TLRs Layer of mucous T reg cells produce IL-10 and TGFBeta
8
Q
Paneth cells found in
A
Crypts
9
Q
Lymphoid gut tissue drains to
A
Mesenteric lymph nodes
10
Q
Lamina propria
A
T cell rich area of the gut
11
Q
Dendritic cells of the gut
A
Extend across the epithelial layer to capture antigen from the lumen of the gut
