Immunoglobulin effector function Flashcards
1
Q
what are the 2 ways T cells provide help to B cells
A
1) co-stimulatory signal through ligation of CD40 and CD40L
2) secretion of cytokines which aid in the induction of isotype switching
2
Q
what are the 5 immunoglobulin classes
A
IgG
IgA
IgM
IgE
IgD
3
Q
All B cells begin by making which immunoglobulin
A
IgM
4
Q
which immunoglobulins do memory cells produce
A
IgG
IgA
IgM
IgE
5
Q
what is isotype switching
A
Isotype switching is a crucial process that occurs in B cells during their maturation and differentiation, allowing them to produce antibodies of different immunoglobulin classes (isotypes) while maintaining the specificity for the same antigen.
6
Q
A