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Terminology & Lists > IMMUNO (CDs) > Flashcards

IMMUNO (CDs) Flashcards

1
Q

CD3

Function, Drug Against?

A

Signal Transduction (in assoc w TCR)

DRUG AGAINST = Muromonab-CD3 / OKT3

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2
Q

CD2

Function?

A

Adhesion molecule.

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3
Q

CD4

Function, Path?

A

Coreceptor for MHC II.

PATH:
- Receptor for HIV

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4
Q

CD8

Function?

A

Coreceptor for MHC I.

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5
Q

CD14

Function?

A

Binds LPS (lipopolysaccharide / endotoxin) receptor on Gram- bacteria.

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6
Q

CD16

Function?

A

Binds IgG (Fc receptor).

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6
Q

CD19, 20, 21

Function?

A

CD 19 + 20 = Coreceptors w CD21 for B-cell activation.

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7
Q

CD20

Drug Against?

A

DRUG AGAINST = Rituximab

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8
Q

CD21

Function?

A

Receptor for EBV.

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9
Q

CD25

Function?

A

IL2 receptor.

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10
Q

CD28

Function?

A

Binds B7 (costimulatory molecule) on APC.

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11
Q

CD40

Function?

A

Binds CD40 ligand -> Starts Isotype Switch.

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12
Q

CD52

Drug Against?

A

DRUG AGAINST = Alymtuzumab

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13
Q

CD55 (Decay-Accelerating Factor = DAF)

Function?

A

Prevent complement-activation on SELF cells (ie RBCs).

Does this together w C1 Esterase Inhibitor

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14
Q

CD56

Marker For?

A

MARKER FOR:

- NK cells

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15
Q

T Cells

Surface Proteins (3)?

A

S PROTEINS:

  • TCR (binds antigen-MHC complex)
  • CD3
  • CD28
16
Q

Helper T Cells

Surface Proteins (2)?

A

S PROTEINS:

  • CD4
  • CD40 ligand
17
Q

B Cells

Surface Proteins (5)?

A

S PROTEINS:

  • CD19
  • CD20
  • CD21 (receptor for EBV)
  • CD40
  • B7
18
Q

Macrophages

Surface Proteins (3)?

A

S PROTEINS:

  • CD14
  • CD40
  • B7
19
Q

NK Cells

Surface Proteins (2)?

A

S PROTEINS:

  • CD16 (binds IgG)
  • CD56 unique marker for NK cells

Terminology & Lists (12 decks)

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