HEME (Pathological WBC Forms) Flashcards
Auer Rods
Def’n, Seen In?
Peroxidase+ cytoplasmic inclusions in granulocytes and myeloblasts.
SEEN IN:
- AML (esp M3)
Band Cells
Def’n, Reflection Of, Seen In (2)?
Immature neutrophils.
Reflect states of ↑MYELOID proliferation.
SEEN IN:
- Bacterial infections
- CML
Hypersegmented Polyps
Def’n, Seen In?
Neutrophils with 5+ lobes.
SEEN IN:
- Vit B12 / Folate deficiency
Smudge Cells
Def’n, Seen In?
“Smashed” lymphocytes.
SEEN IN:
- CLL
Neutrophils with BILOBED NUCLEI
Seen In?
SEEN IN:
- Pelger-Huet Anomaly
Neutrophils with CEREBRIFORM (convoluted) NUCLEI
Seen In (2)?
SEEN IN:
- Cutaneous T Cell Lymphoma
- Mycosis Fungoides
Neutrophils with HYPERSEGMENTED NUCLEI
Seen In?
SEEN IN:
- Folate def -> Macrocytic Megaloblastic Anemia
Neutrophils with CYTOPLASMIC INCLUSIONS
- > Oval PALE blue inclusions (near cytoplasmic memb)?
- > DARK blue granulations?
- > Large EOSINOPHILIC granulations?
- Sepsis
- Sepsis (toxic granulation)
- Chediak-Higashi Sx
Reactive CD8 T Cells
Seen In?
SEEN IN:
- Infectious Mononucleosis