IMMUNO Flashcards
1
Q
CD surface marker found on all NK cells and binds constant region of IgG
A
CD16
2
Q
CD surface marker that inhibits complement C9 binding
A
CD55
CD59
3
Q
CD surface marker that is an endotoxin receptor found on macrophages
A
CD14
4
Q
Primary immune system cell type involved in host tumor immune surveillance
A
Cytotoxic T cells
5
Q
How might tumor cells induce apoptosis of T cells that would antagonize them?
A
Expressing FasL (death receptor) This is seen in melanoma, hepatocellular CA, etc.
6
Q
Enzyme present in melanoma that generates peptides that are targets for host T cells
A
Tyrosinase
7
Q
Cytokines produced by Th1 cells
A
IL-2, IFN-y
Activation of CD8 and macrophages
8
Q
Cytokines produced by Th2 cells
A
IL-4, Il-5, IL-10
Activation of B cells, Ab production
9
Q
What are the 3 acute phase cytokines?
A
IL-1
IL-6
TNF alpha
