Immunity - Cell Mediated Response

Question 1

What do T-cells respond to?

Answer 1

Antigen presenting cells (APC)

Question 2

Cells mediated response process

Answer 2

1. Phagocytosis
2. Helper T cells have receptors on their surface - can attach to the antigens on APC
3. Once attached - activates T helper cells - divide by mitosis to replicate + make a larger number of clones
4. Cloned helper T cells can differentiate into different cells

Question 3

What type of cells can cloned helper T cells differentiate to?

Answer 3

• can remain as helper T cells and activate B cells
• stimulate macrophages to perform more phagocytosis
• memory cells
• cytotoxic T cells

Question 4

What are cytotoxic T cells and what do they do?

Answer 4

• can destroy infected and abnormal cells
• releases perforin - embeds in cell surface membrane
• makes pore hole so that any substances can can leave and enter the cell
• can cause cell death