Immunity - Capter 7 Flashcards
3 lines of defense
- Physical barrier (skin)
- Innate/ non -specific (cells)
- Specific immunity (white blood cells)
non specific immunity
General protection - tears and mucus
Specific immunity
Involves memory and the ability to respond to specific threats
Inherited vs acquired immunity
Through mother vs experience
Protein bodies critical to immunity
Anti-bodies and complements
Antibody - structure and purpose
Y shaped proteins with 3 binding regions Antigen specific tips Neutralize or collect enemy cells Promote phagocytes (clump and attract) Complement fixation
Complement fixation
When antigens attach to antibody expose complement -binding sites which activate complement proteins to form donut complex that kills invader.
Phagocytes
White blood cells
From bone marrow
neutrophils and monocytes
Macrophage
Monocytes increase in size and produce granules
Secrete substances that attract other wbc
Lymphocytes
Most numerous, produce antibodies
Circulate in body fluids
Two types - B and T
B cell
Type of lymphocyte, from bone marrow, containing antibodies, clones to form numerous immature b cells
When iB meets specific antigen, divides into plasma and memory
Plasma vs memory cell
Both activated B, plasma = cloned antibodies
Memory= stay in lymph nodes with antibodies
T cells
Lymphocytes
Develop in thymus, live in lymph nodes, specific antigen will activate: kill directly or attract macrophage
3 hypersensitivities
Allergy - sensitive to harmless environmental factors
Autoimmune - inappropriate response to self- antigens
Isoimmunity - reaction to baby or transplant antigens
Allergy - 3 main types
Food
Chemicals
Inhaled allergens
Treatment allergies
Esters to calm (clary sage, lavender, RC)
Respiratory (Euc, tea tree, pine)
Anti-inflammatory (lemon, peppermint, lavender)
Frank base
Skin: sub helichrysum, rose
Chrohn’s
Inflamed intestinal tract
Cramp, fever,fatigue,pooping, joints, mouth sores and gums
Analgesic (lavender, peppermint)
AI (esters)
AS (esters basil)
Calm (esters)
Graves
Over-active thyroid (hyperthyroidism)
Anxiety, eyeballs, fatigue, hot and sweaty, insomnia, sob,
Anti-inflammatory (Esters)
calm CNS ( sesquiterpines myrrh)
Respiratory (Euc, pine)
Lupus
Multi system
Analgesic (monoterpine, )
AI (sesquiterpine, sesquiterpine alcohol, aldehyde)
soothing (esters)
MS
Brain and spinal - myelin sheath damage
Muscle - balance, numbness, coordination, weakness Bowel: constipation, leaks Eyes: discomfort, loss, blurry Brain: foggy, dizzy, hearing, speech Sexual
Calm CNS - sesquiterpine and aldehyde
Muscle - pain (pine)
Neuro/eye - Frank, helichrysum
Sexual - clary sage
Rosemary, sandalwood, lemongrass, geranium
Rheumatoid arthritis
Inflammation of joints (AI sesquiterpine patchouli clary sage and sesquiterpine alcohol basil sandalwood myrrh) aldehyde (lemon grass, lemon euc). Esters -AS
Fir, myrrh, euc citriodora, basil, (aldehyde - AO)
Celiac
Reacting to gluten
Gas, pooping, anemia, dental and bones, fatigue, depression
Stomach - ginger, fennel, peppermint, caraway
Massage and foot baths
Immunodeficiency disorders
Disruption of b/t cells
Congenital - born with it
Acquired - HIV CANCER spleen removed, diabetes,chronic fatigue, candida
Immunosuppresed - drugs (chemo and steroids)
HIV/AIDS
Rna forms outta own DNA
Immune system fails
HIV can lead to AIDS
Alcohol and aldehyde to fight infection AO
Ester/sesquterpine Anti-inflammatory
Chronic fatigue syndrome
Prolonged fatigue (6 mo +) Extreme
Uplift (esters), Anti-inflammatory (sesquiterpine ester) analgesic (monoterpine)
Fibromyalgia
Pain to joints, muscles and tissues
Uplift (bergamot)AI (sesquiterpine aldehyde)
Ao (esters
Psychoneuroimmunology
Immunity and resistance to disease are linked to attitudes and behavior
Nose-cns-immumity