Immunisation Flashcards
Where are B cells found?
Bone marrow
Where are T cells found?
Thymus
What cell produces antibodies?
B cell
Give some examples of passive immunity
Mother to unborn baby via placenta
From person e.g. blood donor
What is passive immunity?
Transfer of pre-formed antibodies
What is ‘herd immunity’?
Protects unvaccinated individuals through having a sufficiently large portion of the population vaccinated
What are live virus vaccines?
Attenuated organism, replicates in host
Define attenuated
Reduced in virulence
What are the different types of inactivated vaccine?
Suspension of killed organisms
Subunit vaccines
Conjugate vaccines
What are contraindications to live vaccines?
Immunosuppression
Pregnancy
What are some contraindications to getting vaccinated?
Confirmed anaphylaxis
Egg allergy (certain vaccines)
Severe latex allergy
Acute/evolving illness
What immunisations are given in childhood?
DTaP/IPV/Hib/HBV Men B Rotavirus PCV MenC/Hib MMR DTaP/IPV Flu Td/IPV HPV MenACWY
What vaccines are given >65yrs?
Flu
PPV
What vaccines are given over 70?
Zoster
What does the DTaP vaccine protect against?
Diptheria
Tetanus
Pertussis