Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Year 2 Child health > Growth and Puberty > Flashcards

Growth and Puberty Flashcards

1
Q

How far a part are centile lines spaced?

A

2/3 of a standard deviation a part

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

When does puberty occur?

A

When secretion of gonadotrophin releasing hormone (GnRH) increases so that pulsatile secretion of luteinizing hormone (LH) increases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Where is GnRH secreted from?

A

Hypothalamus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What cells does LH stimulate in boys and what do these cells produce?

A

Leydig cells

Testosterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Where does FSH bind in boys and what does this stimulate?

A

Sertoli cells to enhance spermatogenesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What modulates LH secretion in boys?

A

Testosterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What exerts a negative feedback on FSH secretion?

A

Inhibin B from Sertoli cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What does LH stimulate in girls?

A

Proliferation of follicular and thecal cells

During the follicular phase of the menstrual cycle it induces androgen secretion by theca cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What does FSH do in girls?

A

Induces proliferation of granulosa cells
Increases expression of LH receptors on granulosa cells
Enhances aromatase activity so that androstenedione is converted to oedstradiol
Increases progesterone production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What does oestradiol (E2) act on to cause proliferation of follicular cells in addition to inducing secondary sexual development?

A

FSH receptors on granulosa cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Where is inhibin B produced?

A

Granulosa cells in small antral follicles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Where is inhibin A produced?

A

Large antral follicles and by the corpus luteum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What do inhibins have a role in?

A

Inhibit FSH secretion

Dominant follicle selection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How is puberty staged?

A

Tanner staging

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is thelarche?

A

Breast budding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is adrenarche?

A

Body hair and odour

17
Q

What is true central precocious puberty?

A

Normal pubertal development occuring abnormally early

18
Q

What are the cut off ages for precocious puberty in girls and boys?

A

Girls - 8yrs

Boys - 9yrs

19
Q

What are the cut off ages for pubertal delay?

A

13yrs girl

14yrs boy

20
Q

A patient presents worrying that they have a growth problem. What questions should you ask?

A 
ICE
Birth
PMHx
Pubertal symptoms
FHx
-Parental heights
-Parental puberty
21
Q

What should you examine on a patient presenting with a growth problem?

A

Height, weight, height velocity
Signs suggestive of pathology
Pubertal status

22
Q

What investigations should you do for a patient presenting with a growth problem?

A

Bloods

  • gonadotrophins
  • growth factors
  • testosterone/oestradiol
  • thyroid
  • karyotype
  • etc

Bone age

Dynamic function tests

MRI brain, USS uterus

23
Q

What is genetic short stature?

A

Healthy, normal child that has inherited short stature from parents

24
Q

What is a constitutional growth delay?

A

Late maturation causing short stature

Year 2 Child health (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions