Development of nervous system

Question 1

When does human brain development begin?

Answer 1

3rd week post conception

Question 2

What is the time period of embryonic development?

Answer 2

0-9weeks

Question 3

What is the time period of fetal development?

Answer 3

9-40/42 weeks

Question 4

What is gastrulation?

Answer 4

The development of the 3 layered embryo

Question 5

What are the 3 layers formed in gastrulation?

Answer 5

Ectoderm
Mesoderm
Endoderm

Question 6

What does the ectoderm go on to form?

Answer 6

Skin, nails, hair and neural tissue

Question 7

What does the mesoderm go on to form?

Answer 7

Muscle, bone, cartilage and vascular system

Question 8

What does the endoderm go on to form?

Answer 8

Gut and resp system

Question 9

When does the neural tube form?

Answer 9

Days 20-27

Question 10

What lines the inside of the neural tube?

Answer 10

Neural progenitors

Question 11

Where is the high concentration of Pax6?

Answer 11

Anterior /rostral pat of brain

Question 12

Where is the highest concentration of Emx2?

Answer 12

Posterior/caudal part of brain

Question 13

When do the primary sulci develop in the brain?

Answer 13

Week 8-26

Question 14

Where do progenitor cells remain during development?

Answer 14

Ventricular zone

Question 15

Where do neurones migrate to in the fetal period?

Answer 15

Neocortex

Question 16

When does myelination occur?

Answer 16

Postnatally

Question 17

What is anencephaly?

Answer 17

Absence of a major portion of the brain that occurs during embryonic development

Results from neural tube defect

Question 18

What is spina bifida?

Answer 18

Neural tube birth defect/

Bones of the spine don’t form properly around the spine - gap in spine

Question 19

What is the name of the predominant myelin protein persent in the CNS?

Answer 19

Transmembrane proteolipid protein encoded by PLP1

Question 20

What chromosome is the PLP1 gene found on?

Answer 20

X chromosome