Immune system VI - Transplantation Flashcards
1
Q
Why does transplant rejection occur?
A
The organ is fundamentally different
MHC is different
2
Q
Why are MHC so diverse?
A
Expression is co-dominant
3
Q
What is the only cure for transplantation rejection?
A
Removal of the antigen
4
Q
Name TWO common interventions
A
Immunosuppressants
Azathioprene - antiproliferative drugs
Ciclosporin - Inhibitors of lymphocyte signalling
5
Q
What are the consequences of immunosuppression?
A
Increased sensitivity to infection
6
Q
Name THREE methods of managing immunosuppressed patients
A
Close monitoring
Antibiotics
Antivirals
