Immune system III - Vaccine formulation

Question 1

What are the FIVE features of an effective vaccine?

Answer 1

Safe
Protective
Sustained protection
Induces an appropriate immune response
Practical considerations like cost and safety

Question 2

Name the FOUR components of vaccines and give examples where appropriate

Answer 2

Antigen
Adjuvant - aluminium salts
Stabilisers - polysorbates
Preservative - Thimerosal

Question 3

What is the role of the antigen in a vaccine?

Answer 3

Stimulates the immune response

Question 4

What is the role of the adjuvant in a vaccine?

Answer 4

Enhances the immune response in subunit vaccines

Question 5

What is the role of stabilisers?

Answer 5

Prevents physical/chemical degredation of antigen

Question 6

What is the role of preservatives?

Answer 6

Prevention of microbial growth