immune system & lymph organs Flashcards
provides defense or immunity against infectious agents ranging from viruses to multicellular parasites.
Immune system
2 partially overlapping lines of defense against invaders and/or potentially harmful cells
Innate and Adaptive immunity
lymphocytes are formed initially in ______
Primary lymphoid organs
what are examples of primary lymphoid organs
thymus and bone marrow
most lymphocyte activation and proliferation occurs in _______
secondary lymphoid organs
examples or secondary lymphoid organs
lymph nodes, spleen, and diffuse lymphoid tissue found in : digestive system, tonsils, peyer patches, and appendix
immune cells are located diffusely where
digestive, respiratory, or urogenital mucosae
involves immediate, non-specific actions, including physical barriers that prevent infections or penetrations of the host body
innate immunity
________ on leukocytes allow the recognition and binding of surface components of such invaders
Toll-like receptors (TLR’s)
destroys various unhealthy host cells
Natural killer cells
specific regions lower the pH locally to either kill entering microorganisms directly inhibit their growth
HCl and organic acids
short cationic polypeptides that kill bacteria by disrupting the cell walls
defensins
hydrolyzes bacteria cell wall components, thus killing those cells
Lysozymes
system of proteins in blood plasma, mucus, and macrophages that react with bacteria surface components to aid removal bacteria
competent
paracrine factors that signal NK cells to kill cell and adjacent cells to resist viral infection.
interferons