immune system Flashcards
soluble recognition molecules (innate immune system)
MBP / acute phase protein
cell-associated recognition molecules (innate immune system)
PRR / PAMPs/ cytokins receptor
mast cell is a (type of cell)
granulocyte
neutrophils is a (type of cell)
phagocyte/ granulocyte
basophils is a (type of cell)
granulocyte
eosinophils is a (type of cell)
phagocyte / granulocyte
monocyte
phagocyte / antigen-presenting cell
dendrite
phagocyte / antigen-presenting cell
macophage
phagocyte / antigen-presenting cell
explain type I hypersensitivity
IgE—surface of the mast cell –reexpose to the same antigen—release of the inflammtory factors
immediate
explain type II hypersensitivity
antibodies binds to the cell surface (not IgE)—mark it for further destory (by complement or macrophage)
autoimmune disease
IgG/ IgM
explain type III hypersnesitivity
antibodies bind to the free antigens
serum sickness
explain type IV
T-cell mediated
contact dermatitis
delayed reaction
autoimmune disease
fail to identify self
autoreactive T cell
antibodies
transplant rejection
identify non-self (MHC polymorphism)
IV sensitivity
