Immune responses to viral infections Flashcards
1
Q
Name 4 DNA viruses
A
Poxvirus (smallpox), herpesvirus, adenoviruses (sore throat, conjunctivitis), papillomaviruses (warts)
2
Q
Name 4 RNA viruses
A
Orthomyxoviruses (influenza), paramyxoviruses (measles, mumps, respiratory tract infections), rubella virus, retroviruses (AIDS, T cell leukaemia)
3
Q
Which protein does RIG-1 interact with to activate TFs to increase type 1 IFN
A
MAVS
4
Q
Which protein recognises long dsRNA
A
Melanoma Differentiation factor 5 (MDA5)
5
Q
Which enzymes activate the latent endonuclease (RNaseL)
A
The dsRNA-dependent enzyme 2’,5’-oligoadenylate synthetase
6
Q
Which protein phosphorylates and inhibits eukaryotic initiation factor (eIF)-2alpha
A
Protein Kinase R
