Immune Response Flashcards

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1
Q

1st line of defense (generalization)

A
  • non-specific
  • Physical
  • Surface protection that keep microbes from getting into the body
    1. Skin
    2. Lysozymes
    3. HCl
    4. Cilia
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2
Q

2nd line of defense (generalization)

A
  • Non-specific
  • Chemicals that comes immediately into play if things makes it past the 1st line
  • Include macrophages, neutrophils, and monocytes
  • Cell-mediated immunity
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3
Q

3rd line of defense (generalization)

A
  • Specific
  • Antibodies that are developed uniquely for each microbe through action of specialized WBC’s
  • Antibody-Mediated Immunity
  • Lyphocytes : B cells and T cells
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4
Q

HCl

A
  • Stomach Acid

- Destroy invading microbes carried in food

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5
Q

Skin

A
  • Protective barrier

- Acidic enough to inhibit growth of microbes

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6
Q

Lysozymes

A
  • Enzymes produced in tears, salvia, mucus, and perspiration
  • Destroy cell walls of bacteria
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7
Q

Cilia

A
  • Found in respiratory tract
  • Trap microbes and foreign debris
  • Cough/sneeze to expel
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8
Q

Role of monocytes in 2nd line of defense

A
  • Move into tissues and become macrophages and phagocytose foreign invaders
    - Extend protrusions(pseudopods), that attach to surface of invading microbe and engulf and destroy it bu enzymes
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9
Q

Role of neutrophils in 2nd line defense

A
  • Move into infected tissues by a process called chemotaxis
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10
Q

Define Chemotaxis

A

Chemical signals given off by cells that have been damaged by microbes and eat microbe and damaged WBC

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11
Q

Pus

A

Remaining fragments of protein, dead WBC and digested invaders

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12
Q

Inflammatory Response

A
  • Initiated by tissue damage due to physical injury

- A non-specific immune system response resulting in swelling, redness, heat and pain

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13
Q

Fever

A
  • System wide defense to more severe damage or infections
  • When neutrophils or macrophages digest invaders, they release chemicals which go to your brain and increase your temperature, which kills invaders
  • Makes it difficult for harmful bacteria to survive
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14
Q

B cells

A
  • Mature in bone marrow
  • B cells
  • Memory B cells
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15
Q

T cells

A
  • Mature in thymus gland
  • Helper T cells
  • Killer T cells
  • Suppressor T cells
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16
Q

Helper T cells

A

Identify foreign invaders and sends information to B cells/plasma cells

17
Q

B cells and plasma cells

A

Produce antibodies that are specifically for the antigen

18
Q

Killer T cells

A

Puncture cell membranes of infected cells

19
Q

Suppressor T cells

A

Turn off immune system

20
Q

Memory B cells

A

Retain information about shape of antigen for future infections

21
Q

Antibodies

A
  • Y shaped proteins that recognize foreign substances and act to neutralize or destroy them
  • Specific to invader
22
Q

Antigen-antibody complex

A

Antibody binds to antigen to create complex which gets destroyed by macrophages to prevent them from entering cells