Immune 1

Question 1

All immune cells arise from

Answer 1

Bone marrow hematopoietic stem cells

Question 2

Granulocytes arise from

Answer 2

Myeloid progenitor

Question 3

Phagocytosis, opsonization,ADCC,APC, secretion of cytokines,complement system

Answer 3

Macrophages

Question 4

APC, They express class I and II MHC Present in Blood, LNs, Epithelial cells 
Examples: Langerhan cells (skin)

Answer 4

Dendritic cells

Question 5

Released from bone marrow as undifferentiated and differentiate in the
tissues, Morphology and function similar to basophils , Have Fc receptors for IgE (FceRs), Play a very important role in the allergic response, Produce a variety of cytokines

Answer 5

Mast cells

Question 6

Granulocytes, Three cell types: neutrophils, eosinophils and basophils, based on their staining.Important for removal of bacteria and parasites from the body. They engulf these
foreign bodies and degrade them using their powerful enzymes.

Answer 6

PMNs

Question 7

contains bactericidal enzymes Efficient phagocytes, receptor for Fc region of IgG & C3b

Answer 7

Neutrophils

Question 8

APC

Answer 8

Dendritic
Bcells
Macrophages

Question 9

  Have receptors for Complement, Classically seen with:

ü Atopic allergies ü Worm infections ü Collagen Vascualr diseases ü Neoplastic disorders ü Skin rash

Answer 9

Eosinophil

Question 10

highly toxic to worms

Answer 10

Major Basic Protein (MBP)

Question 11

Only present in the bloodstream
They play a major role in the allergic response release histamine, Has Fc receptors for IgE (FceRs)

Answer 11

Basophils

Question 12

Phagocytes

Answer 12

All EXEPT T,B, and NK

Question 13

Different maturational stages of lymphocytes can be distinguished by

Answer 13

their expression of membrane CD molecules (CD = Cluster of Differentiation)

Question 14

CD45+, CD3+

Answer 14

T lymphocytes

Question 15

CD45+, CD3+, CD4+

Answer 15

T helper

Question 16

CD45+, CD3+, CD8+

Answer 16

T cytokines

Question 17

CD45+, CD19+

Answer 17

B lymphocytes

Question 18

CD45+, CD16+, CD56+, CD3-

Answer 18

NK

Question 19

CD45+, CD14+

Answer 19

Monocytes

Question 20

CD45+, CD15+

Answer 20

Granulocytes

Question 21

CD5+

Answer 21

B1 self renewing and innate w high IgM

Question 22

CD-

Answer 22

B2 adaptive

Question 23

The measure of the total binding strength of an antibody at every binding site is termed

Answer 23

Avidity

Question 24

Mainly in innate immunity, non specific, Recognize Foreign Ag independent of MHC

Answer 24

NK