Concepts Flashcards
Virus Associated Proteins (VAPs) or ligands ( in adsorption)
binds to host cell receptors.
Viropexis
entry of virus into host cell
Endocytosis: entire virus is engulfed and
enclosed in a vacuole or vesicle
Non-enveloped viruses:
Fusion: with plasma membrane releasing
nucleocapsid into the cell cytoplasm
Enveloped viruses:
Uncoating may occur;
- cell surface ———-
- cytoplasm——-
- nucleus————
Bacteriophages
Poliovirus
Herpes
It is the period after penetration during which no infectious
virus can be detected inside the host cells. + synthesize viral components
Eclipse
Nuclei acid in RNA@——and in DNA@——
- Cytoplasm (RNA V except some myxoV)and PROTIEN
- Nucleus (DNA viruses, except poxV)
Assembly aka——
In herpes @
In polioviruses@
In enveloped viruses@
Morphogenesis
Nucleus (vesicle and fuse).
Cytoplasm (budding)
Membrane
- release via budding through plasma membrane “exocytosis”
- environmentally reliable and sensitive
- does not need to kill
- wet during transition in large droplets
Enveloped viruses
- environmentally stable
- resistant
- survive in GIT
- spread hand to hand
- must kill to spread
Naked virus
Viral growth curve
Inculcation -eclipse -burst
Max Number of violins released per bacterium
Burst size
-RNA only
– Small genome
– Do not code for protein
– in plants
Viroids
– Contain host cell DNA instead of viral DNA when host DNA
fragmented and incorporated within the capsid
– Can infect cells, but not replicate
Pseudovirions
-Infectious particles
– Protein only
– Do not contain any nucleic acid
– Cause slow diseases
Prions
