Immediate Skin Test Flashcards

1
Q

Type on Gel and Coombs

A

Type I

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2
Q

Type I vs Type IV

A

Type I - IgE mediated

Type IV - T cell mediated

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3
Q

contraindications to Type I Skin Test

A
Severe asthma attack in past two weeks
antihistamines
pregnancy
longtime steroid use
beta blockers
certain chronic medical conditions
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4
Q

Prick Advantage

A
Safer than ID
Minimal systemic absorption
faster
less tedious for tech
Less discomfort for patient
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5
Q

Disadvantage of skin prick test

A

cross contamination

cross reaction

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6
Q

Prick Skin Test Positive Control

A

Histamine 2.75mg/mL

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7
Q

Prick Skin Test Negative Control

A

Diluent used in extract

  • HSA
  • Glycerin
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8
Q

Extract Strengths prick test

A

10,000-20,000 pnu/mL

1:10 or 1:20 w/v

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9
Q

Types of prick device

A

Dermapick (plastic)

Quintip (metal)

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10
Q

How long after skin test do you read?

A

15 minutes

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11
Q

Dermapick vs Quintip placement

A

Dermapick - 45 degress

Quintip - 90 degress

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12
Q

how is prick skin written

A

wheal x flare by widest size

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13
Q

What is often considered postive on test?

A

3mm +

Must be determined by physician

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14
Q

What if negative control has wheal and flare of 3mm?

A

adding requirement that allergent test have wheal size of 3mm more than negative control

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15
Q

false postive reactions

A

technician error

  • excessive strength of antigen admin
  • excessive dose
  • cross contamination

dermagraphic skin

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16
Q

false negative reactions

A

improperly prepared/stored extract
patient took antihistamines
technician error - improper placement
intrinsic factor (leather skin)

17
Q

ID Advantages

A

more sensitive

less chance of cross contamination

18
Q

ID disadvantages

A

more dangerous
more discomfort to patient
more tedious for technician
more irritant/specific reactions

19
Q

extract strength ID

A

100-1000 pnu/mL

1:500 or 1:1000 w/v

20
Q

Positive control ID

A

histamine .275 mg/mL

21
Q

Negative control ID

A

Diluent used in extract

  • Saline with HSA
  • Saline with Phenol
22
Q

Location of prick

A

Forearm

back

23
Q

location of ID

A

Upper arm - from bend of elbow to middle of deltoid

forearm
back

24
Q

ID Procedure

A

Draw up .05mL and inject .02mL under skin

inject enough for 2mm bleb

25
Q

Venom intradermal immediate testing can only be done under supervision of who?

A

Board Certified Allergist

26
Q

Venom extract strength

A

Begin .0001 mcg/mL and gradually increase to 1 mcg/mL

27
Q

Venom Positive Control

A

Histamine .275 mg/mL

28
Q

Venom Negative Control

A

Diluent used in extracts

- saline with HSA

29
Q

Venom test areas

A

upper arm
forearm
back