Imaging Flashcards
How far does an F18 positron travel in water?
0.5 mm
What is the post-injection uptake period for FDG PET?
1 hr
What is a typical dose of FDG PET?
10-20 mCi
What are the 2 broad techniques for automated image registration?
geometry (detects/aligns edges of objects) and intensity (compares the intensity of the voxels themselves) -based metrics
What kind of image registration metric is best for aligning CT to MRI?
mutual information - a special type of intensity-based metric needed because the absolute intensity of MRI and CT differ greatly, and the greater soft-tissue contrast in MRI creates more/different edges making geometry-based registration hard
How does a mutual information registration algorithm work?
tries to minimize the number of voxel-intensity pairings rather than trying to minimize the difference between the voxel intensities themselves
What is the pulse sequence for T1 MRI imaging?
short-short (TR ~ 500 ms, TE < 15 ms)
what is T1 imaging used for in radiotherapy?
to assess nodal invasion
What is the pulse sequence for T2 MRI imaging?
long-long (TR ~ 2000 ms, TE ~ TR)
How to tumors appear on a T2 image?
they tend to be bright (not always, but usually)
What is the pulse sequence for proton density weighted MRI?
long-short
What is T1 relaxation in MRI?
longitudinal relaxation - spin-lattice - the amount of time it takes the protons to realign with the magnetic field (to regrow to 63% of the max value)
What is T2 relaxation in MRI?
transverse relaxation - the amount of time it takes the transverse signal to fade away (to decay to 37% of the max value) after relaxation
What is TR in MRI?
the amount of time between excitation RT pulses
What is TE in MRI?
the time between excitation and signal acquisition