Images Flashcards
What cell is the arrow pointing to?
This is a reticulocyte
you can tell because its larger cell with blueish cytoplasm due to RNA
What does this image show?
immature RBC and tear drop cells
suggets problem with bone marrow production
What does this bone marrow biopsy show?
aplastic anemia and replacement of normal cellular bone marrow with fat
What does this bone marrow biopsy show?
hypocellular = aplastic anemia
What does this peripheral smear show? What causes this?
hypersegmentation of neutrophil –> means megaloblastic anemia
due to folate deficiency or B12 deficiency
What does this bone marrow biopsy show?
asynchrony of nucleus [immature] and cytoplasm [mature] of red blood cell precursors
What does this arrow point to in bone marrow biopsy?
megaloblast with multi lobed nucleus = dyserythropoiesis
sign of megaloblastic anemia
What do the arrows point to in this bone marrow biopsy?
giant metamyelocytes and giant bands
sign of megaloblastic anemia
What does this peripheral blood smear show?
this shows microcytic hypochromic RBCs
What is the difference between these two bone marrow biopsies?
What stain?
left = iron deficient; right = contains normal iron stores
stained with prussian blue
What does this BM asparate show?
Erythroid hyperplasia due to hemolysis
What type of cell do you see in this smear?
2 diseases associated
spherocyte
sign of autoimmune hemolysis, hereditary spherocytosis
What type of cell do you see in this smear?
2 types of anemia
schistocyte
microagniopathic anemia or macroangiopathic anemia
What type of cell do you see in this smear?
sickle cell
What type of cell do you see on this smear?
5 types of diseases associated
target cell
sign of too little hemoglobin or too much membrane
- HbC defect
- Asplenia
- Liver disease
- Thlassemia
- Iron deficiency
What type of cells do you see on this smear?
Acanthocyte
sign of :
- liver disease
- abetalipoproteinemia [cholesterol dysregulation]
What does this smear show?
What are 2 dieases this could be?
polychromasia = presence of reticulocytes
spherocytes
nucleated RBCs
suggests either hereditary spherocytosis or autoimmune hemolytic anemia
What do these RBCs show?
heinz bodies = precipitated Hgb in G6PD deficiency
What does this peripheral smear show?
What type of anemia could this be?
Shows schistocytes = helmet cells
these are fragmented red blood cells in micro/macroangiopathic anemia
What does this peripheral smear show?
sickle cell
What disease does this peripheral smear show?
thalassemia
What does this peripheral smear show?
alpha thalassemia = golf ball appearance of HbH deposition in HbH disease
