IM Flashcards
First and initial approach to patient presenting with chest pain?
Targeted history and PE
Best dx test in chronic stable angina?
ECG
IF NORMAL DO STRESS TEST
First line if treatment for reducing angina?
Beta blockers and CCB
Pharmacologic agents that can be used in stress testing
DAD
DOBUTAMINE
Adenosine
Dipyridamole
Definitive test for CAD
Coronary angiography
Major site of atherosclerotic disease
Epicardial coronary artery
Most common cause of non cardiac chest pain
GI disorder
Drugs for event prevention in stable angina
ACSA
aspirin
Clopidogre
Statins
ACE/ARB
Drugs for relief of angina
Beta blockers and CCB
What to do in a single or two vessel disease with NORMAL LV?
PCI
Indications for CABG
- Three vessel disease
- Two vessel disease that includes LDCA with impaired LV or diabetic
- LEFT MAIN CAD
Next best step after diagnosing a non STE ACS?
Aspirin 4 tabs
Dx test to differentiate NSTEMI and unstable angina?
Cardiac biomarkers
First cardia biomarker to rise in NSTEMI?
Myoglobin
Cardio biomarker to detect reinfarction
CKMB
What are the ABCS of plaque stabilization?
Aspirin, ace, arbs
beta blockers
Clopidogrel
Statins
Difference re pathophysiology of NSTEMI and STEMI?
In NSTEMI plaque rupture resulted in partial occlusion in STEMI there is sudden interruption of blood supply due to total occlusion
Patient presented with a sense of impending doom associated with chest pain. Impression?
STEMI
When can a patient perform sexual activity post MI?
First 1-2 weeks
When can a patient return to work post MI?
2-4 weeks
Most common out of hospital cause of death from STEMI?
Vfib
Most common in hospital cause of death in STEMI?
Pump failure
Patient presented with a tearing chest pain that radiates to the back. Impression?
Aortic dissection
Patient presented with chest pain with dermatomal distribution. Impression?
Herpes zoster
Patient presented with chest pain that is worse in supine and is relieved when sitting upright and leaning forward. Impression?
Pericarditis
Patient presented with chest pain associated with dyspnea and syncope. Impression?
Aortic stenosis (⬆️ cardinal symptoms)
Normal levels for
TCHOL
TG
LDL
HDL
TCHOL <200
TG <150
LDL <100
HDL >40
DOC for hypertriglyceridemia
FIBRATES
DOC and with greatest mortality benefit for hyperlipidemia?
Statins
Drug given to patients with hypertriglyceridemia to prevent pancreatitis
Omega 3 FA
Given to patients with low HDL
Niacin
Most common etiology of HPN?
Primary or essential
Most common cause of secondary HPN
Primary renal disease
Most common cause of mortality in patients with HPN?
Heart disease
How do you dx HPN?
Two or more elevated BP readings in a period of over a week or so
Drug therapy is indicated in hypertensive patients with BP of ?
140/90 or higher
Patient presented with elevated bp with change in sensorium. BP is 230/140. Impression? Most urgent step?
Hypertensive EMERGENCY
START IV MEDS to decrease bp to 25% of initial bp or 160/110-100
Most important mechanism of dyspnea in CHF?
Pulmonary congestion
Most useful test to assess LV function is
2D echogram
Cornerstone of pharmacotherapy in CHF
Beta blockers and ACE inhibitors
Goals of treatment for patients with CHF
Relief of sx
Prevent progression
Reduce mortality
In acute decompensated HF, what is the inotropic agent of choice?
DOBUTAMINE
Most common cause of right sided heart failure?
Left sided heart failure
Patient presented with SYNCOPE, ANGINA and DYSPNEA. Auscultation showede a MIDSYSTOLIC MURMUR. Dx? What is the best INITIAL test?
Dx: AS Transthoracic echocardiogram (TEE)
Patient presented with SYNCOPE, ANGINA and DYSPNEA. What is the most ACCURATE DX test?
Left heart catheterization
Patient presented with SYNCOPE, ANGINA and DYSPNEA. What is the treatment of choice for symptomatic patients?
Aortic valve replacement surgery
Patient presented with a high pitched blowing diastolic murmur over the left sternal border. Dx? Initial dignostic? Tx?
Aortic regurgitation
TEE
SURGICAL AORTIC VALVE REPLACEMENT
Patient presented with a hx of RHD with a low pitched diastolic murmur at the apex. Dx? Chest X-ray finding? Common cause?
Dx: mitral stenosis
Cxr: straightening of the left upper border of cardiac silhouette
MC CAUSE : RHEUMATIC FEVER
Patient diagnosed with Mitral stenosis. What is the most effective treatment?
Balloon valvuloplasty
MS patient presented with onset of ATRIAL FIBRILLATION which is a HALLMARK OF DISEASE PROGRESSION was started with WARFARIN. What is the target INR?
INR 2-3
Patient presented with hpn and a holosystolic murmur at the apex that radiates to the axilla. Dx?
Mitral regurgitation
Patient is a case of MARFAN’s that presented with MIDSYSTOLIC click and systolic murmur that is increased by standing and valsalva. Dx?
Mitral valve prolapse
Patient is a IV DRUG USER presented with a BLOWING HOLOSYSTOLIC MURMUR at the left sternal border. DX?
Tricuspid regurgitation
Most common type of cardiomyopathy
Dilated cardiomyopathy
Leading cause of death in young healthy athletes
Hypertrophic cardiomyopathy
Echocardiography showed a glittering hyperrefractile myocardium. This is typical of?
An amyloid infiltration in restrictive cardiomyopathy
What is a characteristic echocardiographic finding in HYPERTROPHIC CARDIOMYOPATHY?
Systolic anterior motion (SAM)
Features in pericarditis?
Chest pain that is positional
Rub (pericardial friction- pathognomonic)
Effusion that is pericardial
ST segment elevation that is diffuse
(+)etiology -TANS
Management of pericarditis?
Aspirin + omeprazole
NSAIDs or steroids as anti inflammatory
AVOID ANTICOAGULATANTS
Becks triad
Jugular venous distention
Muffled heart sounds
Hypotension
Most urgent step in a diagnosis of CARDIAC TAMPONADE
Echo-guided pericardiocentesis
Best INITIAL test when considering a PAD?
Ankle brachial index (ABI)
Diagnostic is ABI of <0.9
normal >1
PAD <0.9
Severe ischemia <0.5
Gold standard for diagnosis of PAD
Arteriography
First line for symptom improvement if PAD?
Cilostazol
2nd line is PENTOXIFYLINE
Beta blockers that showed evidence for lowering mortality in Heart failure
Metoprolol succinate
Bisoprolol
Carvedilol
Most common cause of chronic cough in a patient who is a non smoker, and not on ACE inhibitors with normal PE and CXR
PAG ang cough >8weeks
Postnasal drip
Asthma
GERD
Samter’s triad
ANA
Aspirin
Nasal polyps
Asthma
Best test to determine reactive airway disease
Metacholine stimulation test
Target SPO2 in asthma?
> 90%
First line of treatment for acute asthma attack
SABA
First line of controller treatment
Low dose ICS
When to step up in asthma control?
2-3 months of uncontrolled or persistent asthma
When to step down asthma mgt?
When asthma attacks are controlled for 3 months
When is it time to start giving ICS in a person dx with asthma
If attacks occur more than 2x a month and the person wakes up from sleep due to an attack more than once a month
Test that CONFIRMS asthma
Spirometry
Best INITIAL test for COPD
Soirometry
Best diagnostic test for COPD in acute exacerbations?
ABG
Target SPO2 in COPD
90% or more
Common risk factor in COPD
Tobacco smoking
Characteristic of asthma
Airway hyper responsiveness
Characteristic of COPD
Airflow limitation/ obstruction
Definitive diagnostic test for COPD
Pulmonary function test or spirometry with FEV1/FVC ratio of <0.7
When to start O2 therapy in COPD?
If SP02 is less than 88% or if 90% with signs if pulmonary hypertension or right sided heart failure
Bacteria more commonly implicated in COPD exacerbations
S. Pneumoniae
H. Influenzae
M. Catarrhalis
Most common atypical pathogens in pneumonia
MCL
Mycoplasma
Chlamydia
Legionella
Most common extra pulmonary TB
TB lymphadenitis
Pott’s disease commonly affects what part of the spine?
Lower thoracic upper lumbar
Tb drug related to peripheral neuropathy
Isoniazid
Tb drugs related to visual impairment
Ethambutol
Cornerstone in diagnosing TB MENINGITIS
Lumbar tap
Gold standard in diagnosing TB MENINGITIS
CSF CULTURE
Most common cause of pleural effusion
LV HEART FAILURE
MC cause of exudative PE
TB
MALIGNANCY IS THE 2nd MC cause
Light criteria
PF:serum protein = >0.5
PF: serum LDH = >0.6
PF LDH > 2/3 upper normal serum limit
Yes = exudative
Patient who worked in ship building came in for annual CXR. Results showed CALCIFIED PLEURAL PLAQUES. Impression?
Asbestosis
*also in tile and brake lining
Patient who worked in the mining industry came in for annual CXR. Results showed EGGSHELL CALCIFICATION . Impression?
SILICOSIS
*also in stone and glass cutting, sandblasting and quarrying
Patient who is an aerospace engineer came in for annual CXR. Results showed nodlues along septal line. Impression?
Berylliosis
*also in nuclear and electronic plants
Patient who worked in a cotton manufacturing company came in for annual CXR. Results showed diffuse infiltrates with hilar adenopathy. Impression?
Byssinosis
A coal worker came in for annual CXR. Results showed progressive fibrosis. Impression?
Coal worker’s pneumoconiosis
DOC for CAP due to a LEGIONELLA infection
Clarithromycin
Features of ARDS
A cute in onset
R ratio of Pa02/FiO2
D iffuse bilateral CXR
S sawn ganz pressure is less than 18mmHg
Most patients are liberated from the mech vent after ARDS when?
From day 7-21
Best initial diagnostic test in an assessment of ARF
ABG
How do you correct hypoxemia in an intubated patient?
adjust mech vent settings to increase oxygenation by increasing FiO2 and increasing PEEP
How do you correct hypercarbia in an intubated patient?
Increase ventilation by increasing RR and increase in tidal volume
What mech vent strategy has shown to improve survival in ARDS?
Low tidal volume
Most appropriate diagnostic test for pulmonary embolism?
Chest ct with contrast
Gold standard in the diagnosis of PE
Invasive pulmonary angiogram
Initial test to rule in or our a PE or a DVT
D-dimer
What is the most urgent step in a cardiogenic shock?
FLUID RESUSCITATION with crystalloids with at least 30cc/kg within 3hours
Vasopressor of choice in shock
Norepinephrine
2nd line = epinephrine
Inotropic agent of choice for shock
DOBUTAMINE
Most serious complication of fluid infusion
Pulmonary edema
Features of tension pneumothorax
P-Thorax
Pleuritic chest pain Tracheal deviation Hyperresonance Onset is sudden Reduced breath sounds and dyspnea Absent fremitus Xray shows collapase
MC sx of DVT
Cramps
Hallmarks of massive PE
Dyspnea
Syncope
Hypotension