ILD

Question 1

Is pulmonary fibrosis malignant?

Answer 1

no

Question 2

what two ILDs do clubbing occur in?

Answer 2

idiopathic pulmonary fibrosis and asbestosis

Question 3

On chest x ray - irregular, reticulo-nodular shadows, often in lower zones?

Answer 3

pulmonary fibrosis

Question 4

what zone of the lungs does IPF usually occur?

Answer 4

lower

Question 5

what is the prognosis of IPF?

Answer 5

most patients die within 5 years

Question 6

what is Pneumoconioses?

Answer 6

A group of disorders caused by inhalation of mineral or biological dusts.

Question 7

what is Simple pneumoconiosis ?

Answer 7

Coal dust deposition within the lung

Question 8

histology of asbestosis?

Answer 8

features of pulmonary fibrosis and honeycomb lung, affecting the lower lobes more commonly

Question 9

which antigens cause Extrinsic Allergic Alveolitis?

Answer 9

• mouldy hay (farmers lung)
• bird faeces (bird fanciers lung)
• cotton fibres (byssinosis)
• sugar cane fibres (bagassosis)

Question 10

farmers lung - which type of immune complex reaction?

Answer 10

type 3 (fork)

Question 11

what is good pastures syndrome?

Answer 11

Glomerulonephritis and respiratory symptoms

Question 12

3 features of good pastures?

Answer 12

haemoptysis, haematuria and anaemia

Question 13

what type of immune hypersensitivity in gps?

Answer 13

type 2

Question 14

which antibody is found circulating in GPS?

Answer 14

anti basement membrane. This causes glomerulonephritis and acts on alveolar membranes

Question 15

what initial appearance would you see on x ray then at later stages in IPF?

Answer 15

ground glass appearance then honeycombing

Question 16

what is the management of IPF?

Answer 16

very few medications have been shown to give any benefit in IPF. There is some evidence that pirfenidone (an antifibrotic agent) may be useful in selected patients (see NICE guidelines)

Question 17

what is the most common form of asbestos related lung disease and generally occurs after a latent period of 20-40 years?

Answer 17

benign pleural plaques

Question 18

Asbestosis typically causes fibrosis in which lobe?

Answer 18

lower

Question 19

latent period in asbestosis?

Answer 19

15-30 years