Ignore Flashcards
what pharmacological class is a medication ending in “lol” belong to?
beta blockers
what are the generic beta blockers you must know?
metoprolol propranolol carvedilol
what pharmacoloigical class is a medication ending in “pril” belong to?
ACE inhibitors
what are the generic ACE inhibitors that you must know?
lisnopril and enalapril
what pharmacological class do medications endingin “cet” belong?
containing acetaminophen
what are the two generic acetaminophen containing meds you must know
Lorcete and percocet
what pharmacological class do medications ending in “pam” belong to?
benzodiazepines
what are the two benzos that you must know?
lorazepam and diazepam
what pharmacological class do meds ending with “zole” belong to?
Proton pump inhibitors
what are the two proton pump inhibitor that you must know?
pantoprazole and lansoprazole
what pharmacological class do medications ending in “cillin” belong to?
penicillins
what are the two penicillins that you must know?
amoxicillin and amplicillin/subactam
what are forms of meds that can be given orally?
capsule, powder, elixir, solution, tablet, syrup, pill, suspension, lozenges,
what are forms of meds that can be given parenteral?
intravenoue, intramuscular, and subcutaneous
what are forms of meds that can be given topically?
lotion, ointment, transdermal patch
what are the four parts of pharmacokinetics?
absorption, distribution, metabolism, and excretion
what is absorption?
from site of entry to blood stream
what is distribution?
drug molecules move from blood stream throughout the body
what is metabolism?
breaking down the drug into metabolites either inactive or active
what is excretion?
removal of the drug and or metabolites from the body
what organ is responsible for excretion of drugs?
Kidneys
what is the order of slowest to quickest absorption?
oral, vaginal/rectal, subcutaneous, intramuscular, buccal/sublingual, endotracheal/inhaled, and intravenous
what are side effects?
things that could happen to someone when taking a medication that are tolerable and predictable
what are adverse effects?
things that could happen to a patient that are life threatening
what are iatogenic effects?
development of a disorder from the use of drug therapy?
what is an example of iatrogenic effect?
neutropenia due to the use of chemotherapy
what is considered a mild to moderate allergic reaction?
rash, fever, diarrhea, vomiting, urticaria
what is the treatment for mild to moderate allergic reactions?
antihistamines and corticosteroids
what is considered anaphylactic allergic reaction?
bronchospasms, CV collapse, and angioedema
what are the treatments for anaphylactic allergic reaction?
iv fluids, epi, bronchodialators, O2, corticosteroids, and antihistamines
what is a histamine?
a chemical released by mast cells involved in allergic reactions.
what is a idiosyncratic effect?
unusual or peculiar response to a drug that may show as overresponse, underresponse, or opposite of expected response
when thinking about drug interactions what is an additive effect?
drugs with similar mechanisms of action produce a greater effect
when thinking about drug interactions what is a synergistic displacement?
drugs with different mechanisms of action potentiate each other????
when thinking about drug interactions what is antagonistic?
combined drugs negate each other taking away effectiveness
when thinking about drug interactions what is inteference?
one drug interferes with the metabolism of another drug which leads to toxicity
when thinking about drug interactions what is displacement?
one drug binds to the site of another drug, displacing it and potentially raising concentration to toxic levels
what developmental considerations should you take into account when giving a pregnant women medication?
it can harm the fetus or it can be passed on through breast milk
what developmental considerations should you take into account when giving a child medications?
- Reduce size and
weight - Reduce body water
- Decreased cardiac
output - Decreased organ
perfusion
what developmental considerations should you take into account when giving older adults medications?
Delayed gastric
motility
* Decrease muscle
mass
* Decreased acid
production and
blood flow
* Impacts drug`
what is the expected age and weight of a healthy individual?
18-65 and 150lbs
what therapeutic class are beta blockers?
antihypertensives
what pharma class are beta blockers?
beta-adrenergic blockers
what are the therapeutic uses for beta blockers?
primarily hypertension
angina/chest pain
tachydysrhytmias
myocardial infaction
heart failure
what medication is used for tacyhdyrhytmias?
the beta blocker metoprolol
what medication is used for heart failure?
the beta blocker carvedilol
what is the pharmacological action of beta blockers
decrease cardiac output
decrease periphreal resistance
decrease cardiac oxygen consumption
will slow AV conduction
how do beta blockers decrease cardiac output?
they block the hormone epinephrine from binding to the receptor which slows heart rate and decreases the force of contraction