Exam #4 Anticoagulants Flashcards
what is the ending for anticoagulants?
in
what are the two anticoagulants?
warfarin and herparin
what is the therapeutic class for warfarin?
anticoagulatns
what is the pharma class for warfarin?
coumarin derivatives
what is the pharma action/how does warfarin work?
antagonizes Vitamin K
prevent coagulation of factor VII and Factor IX
prothrombin
what is the therapeutic use/ what does warfarin treat?
PE
DVT
MI
Prosthetic HV
Chronic afib
what is the adverse effects of warfarin?
hemorrhage….blood in stool or urine…bruising
Hepatitis
Toxicicty
what are the contraindications for warfarin?
pregnancy…breast feeding
low platelet
vitamin K dif
Recent surgery
Liver disorder
what should you monitor when giving warfarin?
INR
what does INR measure?
the level of blood clotting
what is the range for INR?
1 in healthy people…2-3 on anti coag
what should you avoid on warfarin?
eating Vitamin K….leafy greens
what is the therapeutic class for heparin?
anticoagulants
what is the pharmacological class for heparin?
anticoagulatns
what is the pharmacological action/ how does heparin work?
prevents clotting
inactivates thrombin and factor Xa
inhibits fibrin formation