Identify the causes of glomerulonephritis and the resulting changes in glomerular structure and function

Question 1

Glomerulonephritis causes injury to the glomerulus because:

Answer 1

Immunological abnormalities (most common)
Drugs or toxins
Vascular disorders - anything affecting the blood supply for vascular
Systemic diseases
Viral causes
Systemic diseases – diabetes mellitus, system lupus erythematosus, heart failure, HIV related disease

Question 2

Resulting changes

Answer 2

o This can cause decreased glomerular blood flow and filtration rate, nephritic and nephrotic sediments