ID2: Antibacterials Flashcards

1
Q

Inhibit Synthesis/Damage Cell Wall

A

“BBIG FEE”Beta-lactamsBacitracinsIsoniazid (antimycobacterial)Glycopeptides (Vancomycin) & LipoglycopeptidesFosfomycinEthambutol (antimycobacterial)Echinocandins (antifungal)

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2
Q

Inhibit Synthesis/Damage Cell Membrane

A

“PPPAT the Cat LLove” (family MEMBer)Polyene Antifungals (Amphotericin B)Pyrazinamide (PZA) (Anti-mycobacterial)Polymyxins (Colistin)Azole AntifungalsTerbinafine (Antifungal)Ciclopirox (Penlac = Topical Antifungal)Lipopeptides (Daptomycin) & Lipoglycopeptides

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3
Q

Inhibit DNA Synthesis/Metabolism/Damage DNA

A

FluoroquinolonesMetronidazoleFlucytosine (Antifungal)

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4
Q

Inhibit Ribosomal RNA Mediated Transcription/Translation & Protein Synthesis

A

“AMKC, TSOC, MR”AminoglycosidesMacrolidesKetolidesClindamycinTetraclyclinesStreptogramins (Quinupristin/Dalfopristin)Oxazolidinones (Linezolid)ChloramphenicolMupirocin (topical)Rifampin (Antimycobacterial) & derivativesi

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5
Q

Interfere w/ microbial folic acid synthesis

A

TMP/SMX (Sulfonamethoxazole/Trimethaprim)

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6
Q

Beta-lactam antibiotics

A

PenicillinsCephalosporinsCarbapenemsMonobactams

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7
Q

Glycopeptide antibiotics

A

Vancomycin

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8
Q

Lipopeptides Antibiotics

A

Daptomycin

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9
Q

Streptogramins Antibiotics

A

Quinupristin/Dalfopristin - Synercid

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10
Q

Fluoroquinolones “Older” Agents

A

** Non-respiratoryCiprofloxacin

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11
Q

Fluoroquinolones “Newer” Agents

A

**Respiratory agentsLevofloxacinMoxifloxacin

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12
Q

Oxazolidinones Antibiotics

A

Linezolid (Zyvox)

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13
Q

Macrolides Antibiotics

A

ErythromycinClarithromycinAzithromycinFidaxomicin

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14
Q

Tetracyclins

A

DoxycyclineTigecycline

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15
Q

Aminopenicillins

A

Ampicillin - tx for E. faecalis & Listeria monocytogenes(Broad spectrum penicillins2nd generation penicillins)(Amoxicillin)

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16
Q

Antistaphylococcal

A

(Penicillinase resistant)MethicillinNafcillin - tx for MRSA

17
Q

Azole Antifungals - Systemic Agents

A

FluconazoleItraconazoleVoriconazolePosaconazole

18
Q

Echinocandins

A

CaspofunginMicafunginAnidulafungin

19
Q

Ketolides

A

Telithromycin

20
Q

Antipseudomonal

A

Ticarcillin, PiperacillinTicarcillin/Clavulanate, Pipercillin/TazobactamCeftazidime (3rd gen)Cefepime (4th gen)Carbapenems (imipenem, meropenem, doripenem)AminoglycosidesQuinolones (non-respiratory) (Ciprofloxacin)Polymixins - Colistin

21
Q

Miscellaneous Anti-Fungals

A

Amphotericin B (polyene)FlucytosineTerbinafineCyclopirox

22
Q

Extended Spectrum Penicillins

A

Piperacillin - tx for pseudomonas