ID2: Antibacterials Flashcards
Inhibit Synthesis/Damage Cell Wall
“BBIG FEE”Beta-lactamsBacitracinsIsoniazid (antimycobacterial)Glycopeptides (Vancomycin) & LipoglycopeptidesFosfomycinEthambutol (antimycobacterial)Echinocandins (antifungal)
Inhibit Synthesis/Damage Cell Membrane
“PPPAT the Cat LLove” (family MEMBer)Polyene Antifungals (Amphotericin B)Pyrazinamide (PZA) (Anti-mycobacterial)Polymyxins (Colistin)Azole AntifungalsTerbinafine (Antifungal)Ciclopirox (Penlac = Topical Antifungal)Lipopeptides (Daptomycin) & Lipoglycopeptides
Inhibit DNA Synthesis/Metabolism/Damage DNA
FluoroquinolonesMetronidazoleFlucytosine (Antifungal)
Inhibit Ribosomal RNA Mediated Transcription/Translation & Protein Synthesis
“AMKC, TSOC, MR”AminoglycosidesMacrolidesKetolidesClindamycinTetraclyclinesStreptogramins (Quinupristin/Dalfopristin)Oxazolidinones (Linezolid)ChloramphenicolMupirocin (topical)Rifampin (Antimycobacterial) & derivativesi
Interfere w/ microbial folic acid synthesis
TMP/SMX (Sulfonamethoxazole/Trimethaprim)
Beta-lactam antibiotics
PenicillinsCephalosporinsCarbapenemsMonobactams
Glycopeptide antibiotics
Vancomycin
Lipopeptides Antibiotics
Daptomycin
Streptogramins Antibiotics
Quinupristin/Dalfopristin - Synercid
Fluoroquinolones “Older” Agents
** Non-respiratoryCiprofloxacin
Fluoroquinolones “Newer” Agents
**Respiratory agentsLevofloxacinMoxifloxacin
Oxazolidinones Antibiotics
Linezolid (Zyvox)
Macrolides Antibiotics
ErythromycinClarithromycinAzithromycinFidaxomicin
Tetracyclins
DoxycyclineTigecycline
Aminopenicillins
Ampicillin - tx for E. faecalis & Listeria monocytogenes(Broad spectrum penicillins2nd generation penicillins)(Amoxicillin)