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Pharm Q2 > CV: Anti-Angina > Flashcards

CV: Anti-Angina Flashcards

1
Q

Mechanism of Ranolazine

A

late Na+ current –> improve myocardial perfusion(in failing heart, late Na+ current extends the amt of time it takes for muscle to repolarize)** does not affect HR, contractile force or blood vessels

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2
Q

General Mechanism for Nitrates

A

prodrug, converted to NO to vasodilate

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3
Q

Nitroprusside

A

acts in same way as nitrates (through NO)no tolerance bc doesn’t act through mitochondria aldehyde dehydrogenase

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4
Q

Mechanism for Ca Channel Antagonists (Dihydropyridines)

A

vasodilate the arterioles

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5
Q

Mechanism for Ca Channel Antagonists (Non-dihydropyridines)

A

vasodilate the arteriolesat the heart: slow HR & decrease myocardial contraction

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6
Q

Mechanism for Beta-blockers

A

decreased contractile force

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Pharm Q2 (7 decks)

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