ID-Vanco, Lipoglycopeptides and Daptomycin Flashcards
when in vancomycin used?
Gram + MRSA, steptococci and C.difficile
what is the dosing of Vanco used in C.diff and how is it taken?
125 mg tab QID for 10 days
PO
what is the dosing of Vanco used for systemic infections
15 mg/kg Q8-12H using TBW
**if renal impairment, 15 mg/kg Q24H
what is the target trough for Vanco
15-20 mcg/mL
what are the 3 Lipoglycopeptides and their uses
Telavancin
Oritavancin
Dalbavancin
** same as Vanco + Telavancin can be used for HAP and CAP
**ALL IV
what is a BW for telavancin
fetal risk
nephrotoxic
What are the CIs when usin Lipoglycopeptides
use of IV UFH in combo with telavancin
use of IV UFH within the past 5 days
when is Daptomycin used
VRE and similar to Vanco
what are the warnings associated with Daptomycin
rhabomyolysis and myopathy
**monitor CPK esp if on a statin
when should Daptomycin NOT be used
HAP
CAP
MRSA
what is Daptomycin compatible with
NS
LR
What is Daptomycin not compatible with?
DEXTROSE
When is it recommended that Vancomycin not be used
MRSA MIC >2