IBD Flashcards

1
Q

crohns disease clinical presentation?

A

watery diarrhea
perianal disease
abdominal pain

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2
Q

UC clinical presentation?

A

diarrhoea and bleeding

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3
Q

A positive family history is best established factor for IBD development? t/f

A

true

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4
Q

is there a reduced antimicrobial activity in colonic crohns?

A

yes

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5
Q

is smoking a risk factor for both crohns and UC?

A

Aggravates crohns but protects against UC

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6
Q

Can NSAIDS-ibruprofen flare up IBD?

A

YES

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7
Q

US does not start in the rectum and extends distally?

A

no starts at rectum and extends proximally

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8
Q

What are symptoms of UC?

A
Diarrhoea and bleeding
increased bowel frequency 
urgency 
tenesmus-urge for toilet for nothing happens
night rising 
lower adbo pain 
proctitis- can cause constipation
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9
Q

How do you tell the difference between infective diarrhoea and IBD?

A
  • RECENT travel
  • antibiotics
  • NSAIDS
  • Family history
  • smoking
  • skin eyes joint
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10
Q

What criteria is used to determine severity of IBD?

A

truelove and Witt criteria

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11
Q

What is severe UC shown as on this criteria?

A

> 6 bloody stools/24hours and 1 or more of

fever
tachycardia
anaemia
elevated ESR

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12
Q

What assessments can be made for diagnosis of UC?

A

bloods-crp and albumin
plain AXR
endoscopy
histology

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13
Q

What three factors incease risk of colorectal cancer?

A

severity of inflammation
duration of disease
disease extent

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14
Q

Primary sclerosing cholangitis occurs from UC?

A

TRUE

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15
Q

PSC is more likely in UC than crohns?

A

true

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16
Q

symptoms of PSC ?

A

Mostly asymptomatic but there is itch and rigos

17
Q

Does crohns affect people from 15-40?

A

yes

18
Q

What is the distribution of crohns disease?

A

can affect any region of GI tract from mouth to anus. -transmural inflammation

19
Q

What is peri-anal disease?

A
  • recurrent abscess formation
  • pain
  • can lead to fistula with persistent leakage and damaged sphincters
20
Q

What are the different symptoms of crohns in small intestine?

A

abdominal cramps

diarrhoea weight loss

21
Q

crohns in colon symptoms?

A

abdominal cramp-lower abdomen
diarrhoea with blood
weight loss

22
Q

crohns in mouth symptoms?

A

painful ulcers, swollen lips, angular chielitis

23
Q

crohns in anus symptoms?

A

peri-anal pain. abscess

24
Q

what will you measure in bloods for crohns disease?

A

-CRP, albumin, platelets, B12, ferritin

25
Q

What would you find in a histology examination for crohns disease?

A

patchy

granuloma-30-50%

26
Q

What are the three forms of small bowel assessment?

A

barium follow through
small bowel MRI
technetium labelled white cell scan