IBD Flashcards
crohns disease clinical presentation?
watery diarrhea
perianal disease
abdominal pain
UC clinical presentation?
diarrhoea and bleeding
A positive family history is best established factor for IBD development? t/f
true
is there a reduced antimicrobial activity in colonic crohns?
yes
is smoking a risk factor for both crohns and UC?
Aggravates crohns but protects against UC
Can NSAIDS-ibruprofen flare up IBD?
YES
US does not start in the rectum and extends distally?
no starts at rectum and extends proximally
What are symptoms of UC?
Diarrhoea and bleeding increased bowel frequency urgency tenesmus-urge for toilet for nothing happens night rising lower adbo pain proctitis- can cause constipation
How do you tell the difference between infective diarrhoea and IBD?
- RECENT travel
- antibiotics
- NSAIDS
- Family history
- smoking
- skin eyes joint
What criteria is used to determine severity of IBD?
truelove and Witt criteria
What is severe UC shown as on this criteria?
> 6 bloody stools/24hours and 1 or more of
fever
tachycardia
anaemia
elevated ESR
What assessments can be made for diagnosis of UC?
bloods-crp and albumin
plain AXR
endoscopy
histology
What three factors incease risk of colorectal cancer?
severity of inflammation
duration of disease
disease extent
Primary sclerosing cholangitis occurs from UC?
TRUE
PSC is more likely in UC than crohns?
true
symptoms of PSC ?
Mostly asymptomatic but there is itch and rigos
Does crohns affect people from 15-40?
yes
What is the distribution of crohns disease?
can affect any region of GI tract from mouth to anus. -transmural inflammation
What is peri-anal disease?
- recurrent abscess formation
- pain
- can lead to fistula with persistent leakage and damaged sphincters
What are the different symptoms of crohns in small intestine?
abdominal cramps
diarrhoea weight loss
crohns in colon symptoms?
abdominal cramp-lower abdomen
diarrhoea with blood
weight loss
crohns in mouth symptoms?
painful ulcers, swollen lips, angular chielitis
crohns in anus symptoms?
peri-anal pain. abscess
what will you measure in bloods for crohns disease?
-CRP, albumin, platelets, B12, ferritin
