IBD

Question 1

Symptoms of IBD

Answer 1

diarrhoea that lasts longer than 4 weeks
tummy pain
blood or mucus (clear slime) in your poo
bleeding from your bottom
feeling tired all the time
losing weight without trying

Question 2

Diagnosis of IBD

Answer 2

• Endoscopy: examine bowel
• Stool test rule out infection
• Blood test; check for signs of inflammation
• Biopsy during endoscopy

Question 3

Treatment for IBD

Answer 3

• No cure
• Treatment usually includes immunosuppressants to control immune response
• And steroids to reduce inflammation
• SEVERE: Surgery to remove parts of the bowel

Question 4

What part of the GI does crohns effect

Answer 4

Question 5

Definition of Crohns disease

Answer 5

• Chronic inflammation of GIT
• Effects end of small intestine and beginning of large intestine
• Inflammation extends all the way through mucosa to serosa

Question 6

Crohns disease risk factors

Answer 6

Question 7

Crohns disease pathogenesis

Answer 7

Question 8

CD complications

Answer 8

• Narrowing of intestine leads to blockage
• Severe cramping, vomiting
• Haemorrhage
• Infection (abscess)
• Abscess may develop in fistulae
• Anaemia
• Risk of developing colorectal cancer

Question 9

Ulcerative colitis definition

Answer 9

• Inflammation and ulceration of the inner lining of the rectum and colon
• Small ulcers develop on the surface of the intestinal lining - they may bleed or produce puss

Question 10

Major types of UC

Answer 10

Question 11

Risk factors for UC

Answer 11

• Viruses and bacteria
• Diet
• Drugs NSAIDS
• Stress

Question 12

UC complications

Answer 12

• Psychosocial impact: embracement need to poo urgently
• Anxiety and depression
• Toxic megacolon: life threatening
• Intestinal structures: intestine narrows and obstructs passage of bowel contents
• fISTULAS
• ANAEMIA

Question 13

Truelove and Witts severity index

Answer 13

Question 14

Crohn’s versus ulcerative colitis inflammation where?

Answer 14

Question 15

IBD pharmacological intervention

Answer 15

• Most common antibiotics: metronidazole and ciprofloxacin
• Aminosalicylates: first treatment for mild or moderate IBD
• Corticosteroids: stop inflammation
• Immunosupressive e.g. azathiopurine and mercaptopurine, ciclosporin
• Biological medicines: infliximab - expensive, for people who dont respond to steroids or immuno, by IV

Question 16

Symptomatic treatment

Answer 16

• Anti diarrhoeals - codeine phosphate, loperamide
• Bile salt binders - help digestion
• Bulking agent - water to adsorb plant vibre
• Laxatives