IB: Proteins Flashcards
made of long unbranched chain of these amino acids
Protein
a linear chain of amino acids
polypeptides
repeating sequence of atoms along the core of the polypeptide chains
Polypeptide backbone
give amino acids its unique properties
side chains
involved in protein folding
weak covalent bonds
Types if if weak noncovalent bonds on protein folding
-Hydrogen bonds
-electrostatic attrations
- Van der Waals
contains all the information needed for specifying the three-dimensional shape of a protein
amino acid sequence
assist in protein folding
Molecular chaperones
Common folding patterns
- α helix
- β-sheet
Types of folding that leads to α-helix and β-sheet folding patterns?
Hydrogen bonding between N-H and C=O groups
Types of β-sheet structures
- Parallel chains
- antiparallel chains
form from neighboring segments of the polypeptide backbone that run in the same orientation
parallel chains
-from a
polypeptide backbone that folds
back and forth upon itself
-each section of the chain running in the direction opposite of that of its immediate neighbors
Antiparallel chains
Formation of α-helix
- when single polypeptide chain twist around on it self to form rigid cylinder
-Hydrogen bonds between every 4th peptide
-coiled-coil form
4 levels of protein structure
- Primary structure
- secondary structure
- tertiary structure
- Quaternary structure
amino acid sequence
primary structure
hydrogen
bonding of the peptide
backbone; α helices and β sheets
Secondary structure
