Hypoxia, Hypercapnia & Resp Failure Flashcards
Definition of hypoxia
Deficiency of oxygen at tissue level
What is the most common type of hypoxia?
Hypoxaemia (decreased PaO2) arterial pp92
What are the 4 causes of hypoxia?
Hypoventilation
Diffusion impairment
Shunt
V/Q mismatch
How does hypoventilation cause hypoxia?
Increased PaCO2 (arterial pp CO2)
How does diffusion impairment cause hypoxia?
Thickening of membranes/ alveolar membrane
How does shunting cause hypoxia?
Septal defect, perfuming unventilated alveoli
How does V/Q mismatch cause hypoxia?
Most common cause
Occurs in chronic obstructive lung disease
What is hypercapnia?
CONSTITUTES RESPIRATORY DRIVE
CO2 retention and an increased arterial ppCO2
What is the most common cause of hypercapnia?
Hypoventilation
Also sometimes V/Q mismatch
Type 1 resp failure
What happens and causes?
Low pO2 - hypoxia
Normal/low pCO2
Pulmonary embolism
Type 2 resp failure
What happens and causes?
Low pO2 - hypoxia
High CO2 - hypercapnia
Hypoventilation