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CLASS 22010 Endocrine > HYPOTHYROIDISM > Flashcards

HYPOTHYROIDISM Flashcards

1
Q

What endocrine disorder can present with symptoms such as

  1. weakness
  2. cold intolerance
  3. constipation
  4. depression
  5. menorrhagia
  6. hoarseness
  7. dry skin
  8. bradycardia
A

Hypothyroidism

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2
Q

In what thyroid condition may you see delayed return of deep tendon reflexes?

A

Hypothyroidism

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3
Q

In what condition will serum free tetraiodothyronine (aka thyroxine (T4) low and TSH elevation?

A

Hypothyroidism

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4
Q

Primary Hypothyroidism is due to what?

A

thyroid gland disease

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5
Q

Secondary Hypothyroidism is due to a lack of what?

A

Pituitary TSH

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6
Q

True or False

Maternal hypothyroidism during pregnancy results in cognitive impairment in the child

A

True

generally need to increase doses of thyroid replacement hormone (levothyroxine) by 30%

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7
Q

These can all be causes of what?

  1. autoimmune:
    a. Hashimoto’s Disease
    b. Thyroiditis
  2. Subacute (de Quervain’s thyroiditis)(after initial hyperthyroidism)
  3. Iodine deficiency (seen in developing countries)
  4. Genetic thyroid enzyme defects
A

Hypothyroidism with goiter

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8
Q

These can all be causes of what?

  1. Hepatitis
  2. Drugs:
    a. lithium
    b. amiodarone
    c. propylthiouracil
    d. methimazole
    e. phenylbutazone
    f. sulfonamides
    g. interferon
  3. food goitrogens in idodine-deficient areas
  4. Peripheral resistance in thyroid hormone
  5. infiltrating diseases
A

Hypothyroidism with goiter

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9
Q

These can all be causes of what?

  1. thyroid surgery, irradiation, radioiodine treatment
  2. deficiency pituitary TSH
  3. Severe illness
  4. drugs:
    a. lithium
    b. amiodarone
    c. propylthiouracil
    d. methimazole
    e. phenylbutazone
    f. sulfonamides
    g. Interferon a & b
    h. iodine
A

Hypothyroidism WITHOUT goiter

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10
Q

True or False
Radiation therapy to the head-neck-chest-shoulder region can cause hypothyroidism with or without goiter or thyroid cancer many years later

A

True

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11
Q

“Subclinical” hypothyroidism, i.e., clinically euthyroid individual with high TSH, normal t4, occurs commonly in who?

A

Elderly women (10% incidence)

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12
Q

Amiodarone, due to high iodine content, causes clinical hypothyroidism in what percentage of patients?

A

8%

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13
Q

True or False
High iodine intake from other sources may also cause hypothyroidism, especially in those with underlying lymphocytic thyroiditis

A

True

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14
Q

What is caused by interstitial accumulation of the hydrophilic mucopolysacchardies, leading to fluid retention and lymphedema?

A

Myxedema

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15
Q

These can all be early symptoms of what?

  1. fatigue, lethargy, weakness
  2. arthralgias, myalgias, muscle cramps
  3. cold intolerance
  4. difficulty concentrating
  5. constipation
  6. dry skin
  7. headache
  8. weight gain
  9. menorrhagia
A

Hypothyroidism

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16
Q

These can all be late symptoms of what?

  1. slow speech
  2. peripheral edema
  3. pallor
  4. hoarseness
  5. decreased sense of taste, smell, hearing
  6. dyspnea
  7. adsent sweating
  8. amenorrhea or menorrhagia
  9. galactorrhea
A

Hypothyroidism

17
Q

These can be early signs of what thyroid disorder?

  1. thin, brittle nails
  2. thinning of the hair
  3. pallor
  4. poor turgor of mucosa
  5. delayed return of deep tendon reflexes
A

Hypothyroidism

18
Q

These can be late signs of what thyroid disorder?

  1. goiter
  2. puffiness in face and eyelids
  3. thinning of outer eyebrows
  4. tongue thickening
  5. hard pitting edema
  6. pleural, peritoneal, pericardial, and joint effusions
A

Hypothyroidism

19
Q

True or False

Serum TSH is increased in primary hypothyroidism but low or normal in secondary hypothyroidism (pituitary insufficiency)

A

True

20
Q

Is serum triiodothyronine (T3) a good test for routine hypothyroidism?

A

Nope

21
Q

These are lab findings associated with what?

  1. Free T4 may be low or low normal
  2. Serum cholesterol, troglycerides, liver enzymes, creatine kinase, prolactin increased
  3. hyponatremia occurs due to imparied renal tubular sodium reabsorption
  4. hypoglycemia
  5. anemia
A

Hypothyroidism

22
Q

What is the treatment for adult hypothyroidism?

A

Levothyroxine 25-75 mcg/day PO

23
Q

How often should thyroid function tests be repeated for medication titration until TSH is at goal?

A

4-6 weeks

24
Q

What is the disposition of a hypothyroidism patient?

A

MEDEVAC depending on signs and symptoms

may retain if no major issues

25
Q

Long term untreated hypothyroidism can lead to what condition characterized by

  1. hypothermia
  2. hypotension
  3. hypoventilation
  4. hypoxia
  5. hypercapnia
  6. hyponatremia
  7. convulsions
  8. abnormal CNS signs
A

Myxedema Coma

26
Q

True or False

Angina pectoris, congestive heart failure, and cardiac dysrhythmias may be participated by too rapid thyroid replacement

A

True

CLASS 22010 Endocrine (15 decks)

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