Hypothalamus and Pituitary Flashcards
CRH activates
ACTH
ACTH acts on
adrenal cortex
* secretes aldosterone
DA (dopamine) inhibits
prolactin
prolactin
breast development and milk production
TRH activates
TSH
TSH
acts on thyroid
* released thyroid hormone
GHRH (activates) and SS (inhibts)
growth hormone
GnRH activates
FSH and LH
GH function
cartilage and bone growth
protein metabolism
carbohydrate metabolism
lipid metabolism
what does GH increase in protein metabolism
amino acid uptake into cells
protein synthesis
muscle formation
GH is used by athletes to
increase muscle (short half-life)
carbohydrate metabolism (GH)
anti-insulin effects
decrease glucose uptake into cells - increase blood glucose
lipid metabolism (GH)
increase lipolysis (fat breakdown) - increase free fatty acids
treatment of growth hormone deficiency in children
give growth hormone injection
high growth hormone in adults
increase growth of bone where the growth plate does not close off - bones in the face - problem if you take growth hormone to increase muscle