calcium regulation Flashcards

1
Q

calcium function

A

NT and horomone release, muscle contraction, second messanger, bone
* alters nerve activity

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2
Q

hypocalcemia

A

increased nerve excitibility –>muscle tetany –> death

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3
Q

is calcium tightly or loosely regulated

A

tightly

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4
Q

osteoblasts

A

bone deposition
decrease plasma Ca++
largely not regulated

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5
Q

osteoclasts

A

bone resorption
increase plasma Ca++
regulated

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6
Q

calcitonin inhibits

A

osteoclasts

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7
Q

parathyroid hormone (PTH) stimualtes

A

osteoclasts

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8
Q

PTH increases

A
  • plasma Ca++
  • resorption (bone)
  • reabsorption (kidney)
  • absorption (GI)
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9
Q

what type of hormone is PTH

A

peptide

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10
Q

what does PTH stimulate that increases absorption in GI

A

vitamin D3

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11
Q

what happens if both Ca++ and PO4 are increased

A

precipitate (crystals)

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12
Q

where is calcitonin made

A

parafollicular cells in thyroid gland

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13
Q

what type of hormone is calcitonin

A

peptide

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14
Q

high plasma Ca++ causes the release of

A

calcitonin

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15
Q

calcitonin causes decrease in

A

resorption
absorption
readsorption

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16
Q

where is vitamin D3 made

A

kidneys

17
Q

what type of hormone is vitamin D3

A

steroid

18
Q

active vitamin D3 causes an increase in

A
  • resorption
  • absorption
  • reabsorption
  • INCREASED PLASMA CA++
19
Q

decrease in plasma Ca++ means an increase in

A

plasma PO4

20
Q

osteoporosis

A

loss of bone, greater problem in women than in men (menopause)

21
Q

rickets

A

lack of active Vit D3 in children

22
Q

osteomalacia

A

lack of active Vit D3 in adults

23
Q

cause of rickets and osteomalacia

A

lack of vitamin D3 in the diet AND sunlight, or liver/kidney damage

24
Q

a decrease in both plasma Ca++ and PO4 causes

A

poor mineralerizaiton
reduced bone strength