calcium regulation Flashcards
calcium function
NT and horomone release, muscle contraction, second messanger, bone
* alters nerve activity
hypocalcemia
increased nerve excitibility –>muscle tetany –> death
is calcium tightly or loosely regulated
tightly
osteoblasts
bone deposition
decrease plasma Ca++
largely not regulated
osteoclasts
bone resorption
increase plasma Ca++
regulated
calcitonin inhibits
osteoclasts
parathyroid hormone (PTH) stimualtes
osteoclasts
PTH increases
- plasma Ca++
- resorption (bone)
- reabsorption (kidney)
- absorption (GI)
what type of hormone is PTH
peptide
what does PTH stimulate that increases absorption in GI
vitamin D3
what happens if both Ca++ and PO4 are increased
precipitate (crystals)
where is calcitonin made
parafollicular cells in thyroid gland
what type of hormone is calcitonin
peptide
high plasma Ca++ causes the release of
calcitonin
calcitonin causes decrease in
resorption
absorption
readsorption