Hypoparathyroidsim Flashcards
Causes of hypoparathyroidism
Most commonyl surgery around parathyroid galnd
Rare genetics, AI destruction og gland, tumour invasion, raditation or infiltration, hypomagnesaemia and magneeisum depleton
Bloods in hypoPTHism
Low calcium
Low PTH
Elevated phopshate
Normal magnesium and vit D levels
Signs and symptoms of hypoparathyroidsim
Tetany - tiwtch, painful muscle cramps
Perioral paraesthesia
Trousseas sign
Chvosteks sign
Crhonic - depression, cataracts
Can be asymptomatic
What is treatment for hyoparathyroidism
alfacalcidol
What see on ECG in hypoPTHism
Prolonged QT interval
What is trousseas sign
carpal spasm if the brachial artery occluded by inflating the blood pressure cuff and maintaining pressure above systolic
What is chvosteks sign
tapping over parotid causes facial muscles to twitch
What is psuedo hypoparathyroidism
Insensitivity to PTH from target cells due to abnormal G protein
Bloods in pseudo hyoPTH
low calcium, high phosphate, high PTH
What is psuedohypoparathyroidism ass with
Low IQ, short stature, shortened 4th and 5th metacarpals
How diagnose pseudo hypoparathyroidsim
Urinary cAMP = phosphate levels after PTH infusion - neither rise = type I, cAMP rises but not phosphate = type II