Hypoglycemia and Opioid Toxicity Flashcards
What are the indications for the hypoglycemia medical directive?
Suspected hypoglycemia
What are the conditions for dextrose (hypoglycemia m.d.)
Age ≥ 2 years
LOA altered
Hypoglycemia
What are the drugs that can be administered under the hypoglycemia m.d.
Dextrose and glucagon
What are the conditions for glucagon (hypoglycemia m.d.)
LOA altered
Hypoglycemia
What are the contraindication to dextrose (hypoglycemia m.d.)
Allergy or sensitivity to dextrose
What are the contraindications to glucagon (hypoglycemia m.d.)
Allergy or sensitivity to glucagon
Pheochromocytoma
What is dextrose
It’s a liquid formula of carbohydrates
What is glucagon
It’s a hormone (made by the liver) in powder form. It stimulates the liver to move stored glycogen into glucose (glycogenolysis) to be released into the bloodstream.
Produced by pancreas
What are the values of hypoglycemia, normal, and hyperglycemia in an adult
Normal: 4-7 mmol/L
Hypoglycemia: < 4 mmol/L
Hyperglycemia: > 8-9 mmol/L
What are the values of pediatric hypoglycemia
< 2 years old: < 3 mmol/L
≥ 2 years old: < 4 mmol/L
What kind of drug is Naloxone
Non-selective and competitive opioid receptor antagonist
What kind of drug is Buprenorphine
Mixed opioid agonist-antagonist
What is the treatment of dextrose (hypoglycemia m.d.)
D10W
- Dose: 0.2g/kg (2mL/kg)
- Max single dose: 25 g (250mL)
- Dosing interval: 10 minutes
- Max # of doses: 2
D50W
- Dose: 0.5g/kg (1mL/kg)
- Max single dose: 25 g (50 mL)
- Dosing interval: 10 minutes
Max # of doses: 2
What is the treatment for glucagon (hypoglycemia m.d.) for a patient <25 kg
Route: IM
Dose: 0.5 mg
Max single dose: 0.5 mg
Dosing interval: 20 minutes
Max # of doses: 2
What is the treatment of glucagon (hypoglycemia m.d.) for a patient ≥ 25 kg
Route: IM
Dose: 1mg
Max single dose: 1mg
Dosing interval: 20 minutes
Max # of doses: 2