Hyperthyroidism (thyrotoxicosis) Flashcards
What are the aetiologies of hyperthyroidism?
Autoimmune
Toxic multinodular goitre
Toxic adenoma (v rare)
What autoimmune condition causes hyperthyroidism?
Grave’s disease
What is graves disease?
TSH receptor antibodies
- Constantly stimulate thyroid leading to hyperthyroidism
- GOITRE
What causes a toxic multinodular goitre?
Vitamin D deficiency
Symptoms of hyperthyroidism?
Weight loss
Heat intolerance
Sweating
Itch
Signs of hyperthyroidism??
Tachycardia
AF
Palmar erythema
HYPERREFLEXIA
Why does hyperthyroidism cause tachycardia?
TH is permissive to epinephrine
What are the specific signs of graves disease?
Eye disease
- Pretibial myxoedema
What blood tests should be done?
TSH
TH
ESR
Thyroid antibodies
What results would be indicative of Grave’s disease?
TSH low
TH high
Thyroid antibodies detected
What results would indicate secondary hyperthyroidism?
TSH high
TH high
Thyroid antibodies absent
Surgical treatment?
Thyroidectomy
What other treatment can be attempted before surgery?
Radioiodine implant
Carbimazole
What are the complications of hyperthyroidism?
Heart failure
AF
What are the complications of hyperthyroid treatment?
Hypothyroidism
