Hypertension Med Information - Chapter 28 Flashcards

1
Q

Chlorthalidone dosing

A

12.5-25 mg daily

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2
Q

Contraindication for thiazides

A

Hypersensitivity to sulfonamide drugs

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3
Q

Hydrochlorothiazide dosing

A

12.5-25 mg daily

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4
Q

Thiazide side effects

A

Decreased potassium, magnesium, and sodium
Increased calcium, UA, LDL, TG, and BG
Photosensitivity
Impotence

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5
Q

Thiazide monitoring

A

Electrolytes
Renal Function

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6
Q

Thiazide counseling point

A

Take early in the day to avoid having to get up in the middle of the night to go to the bathroom

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7
Q

Which thiazide is available as an IV?

A

Chlorothiazide

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8
Q

Nicardipine dosage forms

A

IV and IR capsule

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9
Q

What is the drug of choice in pregnancy

A

Nifedipine ER

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10
Q

DHP endings

A

-pines

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11
Q

Warning for DHP

A

Hypotension

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12
Q

Warning for Nifedipine IR

A

Do not use for chronic hypertension or acute BP reduction in non-pregnant patients

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13
Q

Monitoring for DHP

A

Peripheral Edema

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14
Q

Which DHP is considered safe to used to lower BP in patients with HFrEF

A

Amlodipine

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15
Q

Side effects of DHP

A

Peripheral edema
Headache
Flushing
Palpitations
Reflex Tachycardia
Gingival Hyperplasia

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16
Q

Clevidipine dosage form

A

Injection

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17
Q

Clevidipine contraindication

A

Allergy to soybeans and eggs

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18
Q

Clevidipine Warnings

A

Hypotension
Reflex tachycardia
Infections

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19
Q

Clevidipine is a lipid emulsion which means _____

A

it will be milky

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20
Q

Verapamil biggest side effect

A

Constipation

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21
Q

Non-DHP side effects

A

Gingival hyperplasia
Constipation

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22
Q

Do you need a washout when switching from ACE to Entresto

A

YES

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23
Q

Do you need a washout when switching from ARB to Entresto

A

NO

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24
Q

ACE BBW

A

Pregnancy

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25
Q

ARB BBW

26
Q

ACE side effects

A

Angioedema
Hyperkalemia
Hypotension
Renal Impairment
Cough

27
Q

If a patient develops a cough with an ACE can you switch them to an ARB?

28
Q

If a patient develops angioedema with an ACE can you switch them to an ARB?

29
Q

Monitoring for an ACE

A

BP
Potassium
Renal function

30
Q

IV ACE

A

Enalaprilat

31
Q

Olmesartan warning

A

Sprue-like enteropathy
Chronic diarrhea with extreme weight loss

32
Q

Amiloride BBW

A

Hyperkalmia (K>5.5)

33
Q

Side effects of K sparing diuretics

A

Hyperkalemia
Increased SCr
Dizziness

34
Q

Spironolactone side effects

A

Gynecomastia
Breast Tenderness
Impotence

35
Q

Beta blockers BBW

A

Do not discontinue abruptly - gradually taper the dose to avoid tachycardia and hypotension

36
Q

Beta Blocker warnings

A

Use caution in patients with diabetes - beta blocker side effects and hypoglycemia have very simular symptoms

Use caution in patients with Raynaud’s disease - simular symptoms

37
Q

Non-selective beta blocker warning

A

Use caution in patients with broncopastic disease

38
Q

What is the IV to PO conversion of metoprolol tartrate?

39
Q

How do you switch between metoprolol tartrate and succinate and vice versa?

A

You have to take the total daily dose and keep it the same.

Example:
- 50mg tartrate BID = 100 mg succinate daily
- 200 succincate daily = 100 tartrate mg BID

40
Q

Selective Beta blockers side effects

A

Bradycardia
Hypotension
CNS effects
Impotence
Cold extremities

41
Q

Nebivolol Contraindication

A

Liver impairment

42
Q

Non-selective beta blockers

A

Propranolol
Nadolol

43
Q

Non-selective beta blocker contraindications

44
Q

Propranolol is highly lipid soluble so it ________ cross the blood brain barrier

45
Q

Other indications for propranolol

A

Migraine prophylaxis
Essential Tremor

46
Q

What other condition are non selective beta blockers used for?

A

Portal hypertension in hepatic disease

47
Q

Catapress TTS dosage

A

0.1 mg/24 hours every 7 days

48
Q

Alpha-2 Adrenergic agonist warning

A

Do not abruptly stop - rebound hypertension

49
Q

Side effects for alpha-2 andrenergic agonist

A

Dry mouth
Fatigue
Dizziness
Somnolence
Constipation
Decreased HR
Hypotension
Impotence
Behavior changes

50
Q

Other uses for alpha-2 adrenergic agonist

A

Kapvay - ADHD
Intuniv - ADHD

51
Q

Methyldopa contraindication

A

MAO inhibitor concurrent use

52
Q

Methyldopa warning

A

Hemolytic anemia

53
Q

Methyldopa side effects

A

Drug induced lupus erythematosus

54
Q

Is methyldopa safe for use in pregnancy

55
Q

Hydralazine dosage forms

A

Tablets
Injection

56
Q

Hydralazine Warnings

A

Drug induced lupus erythematosus

57
Q

Hydralazine side effects

A

Peripheral edema
Headache
Flushing
Paliptations
Reflex tachycardia

58
Q

Minoxidil OTC use

A

Hair growth

59
Q

Minoxidil BBW

A

Potent vasodilator - which can lead to pericardial effusion

60
Q

Minoxidil Side effects

A

Hair growth
Tachycardia
Fluid Retention