Hypertension Med Information - Chapter 28 Flashcards by Katie Lantman

Chlorthalidone dosing

12.5-25 mg daily

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Contraindication for thiazides

Hypersensitivity to sulfonamide drugs

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Hydrochlorothiazide dosing

12.5-25 mg daily

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Thiazide side effects

Decreased potassium, magnesium, and sodium
Increased calcium, UA, LDL, TG, and BG
Photosensitivity
Impotence

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Thiazide monitoring

Electrolytes
Renal Function

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Thiazide counseling point

Take early in the day to avoid having to get up in the middle of the night to go to the bathroom

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Which thiazide is available as an IV?

Chlorothiazide

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Nicardipine dosage forms

IV and IR capsule

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What is the drug of choice in pregnancy

Nifedipine ER

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DHP endings

-pines

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Warning for DHP

Hypotension

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Warning for Nifedipine IR

Do not use for chronic hypertension or acute BP reduction in non-pregnant patients

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Monitoring for DHP

Peripheral Edema

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Which DHP is considered safe to used to lower BP in patients with HFrEF

Amlodipine

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Side effects of DHP

Peripheral edema
Headache
Flushing
Palpitations
Reflex Tachycardia
Gingival Hyperplasia

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Clevidipine dosage form

Injection

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Clevidipine contraindication

Allergy to soybeans and eggs

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Clevidipine Warnings

Hypotension
Reflex tachycardia
Infections

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Clevidipine is a lipid emulsion which means _____

it will be milky

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Verapamil biggest side effect

Constipation

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Non-DHP side effects

Gingival hyperplasia
Constipation

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Do you need a washout when switching from ACE to Entresto

YES

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Do you need a washout when switching from ARB to Entresto

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ACE BBW

Pregnancy

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ARB BBW

Pregnancy

ACE side effects

Angioedema Hyperkalemia Hypotension Renal Impairment Cough

If a patient develops a cough with an ACE can you switch them to an ARB?

Yes

If a patient develops angioedema with an ACE can you switch them to an ARB?

Monitoring for an ACE

BP Potassium Renal function

IV ACE

Enalaprilat

Olmesartan warning

Sprue-like enteropathy Chronic diarrhea with extreme weight loss

Amiloride BBW

Hyperkalmia (K>5.5)

Side effects of K sparing diuretics

Hyperkalemia Increased SCr Dizziness

Spironolactone side effects

Gynecomastia Breast Tenderness Impotence

Beta blockers BBW

Do not discontinue abruptly - gradually taper the dose to avoid tachycardia and hypotension

Beta Blocker warnings

Use caution in patients with diabetes - beta blocker side effects and hypoglycemia have very simular symptoms Use caution in patients with Raynaud's disease - simular symptoms

Non-selective beta blocker warning

Use caution in patients with broncopastic disease

What is the IV to PO conversion of metoprolol tartrate?

1:2.5

How do you switch between metoprolol tartrate and succinate and vice versa?

You have to take the total daily dose and keep it the same. Example: - 50mg tartrate BID = 100 mg succinate daily - 200 succincate daily = 100 tartrate mg BID

Selective Beta blockers side effects

Bradycardia Hypotension CNS effects Impotence Cold extremities

Nebivolol Contraindication

Liver impairment

Non-selective beta blockers

Propranolol Nadolol

Non-selective beta blocker contraindications

Asthma

Propranolol is highly lipid soluble so it ________ cross the blood brain barrier

DOES

Other indications for propranolol

Migraine prophylaxis Essential Tremor

What other condition are non selective beta blockers used for?

Portal hypertension in hepatic disease

Catapress TTS dosage

0.1 mg/24 hours every 7 days

Alpha-2 Adrenergic agonist warning

Do not abruptly stop - rebound hypertension

Side effects for alpha-2 andrenergic agonist

Dry mouth Fatigue Dizziness Somnolence Constipation Decreased HR Hypotension Impotence Behavior changes

Other uses for alpha-2 adrenergic agonist

Kapvay - ADHD Intuniv - ADHD

Methyldopa contraindication

MAO inhibitor concurrent use

Methyldopa warning

Hemolytic anemia

Methyldopa side effects

Drug induced lupus erythematosus

Is methyldopa safe for use in pregnancy

Yes

Hydralazine dosage forms

Tablets Injection

Hydralazine Warnings

Drug induced lupus erythematosus

Hydralazine side effects

Peripheral edema Headache Flushing Paliptations Reflex tachycardia

Minoxidil OTC use

Hair growth

Minoxidil BBW

Potent vasodilator - which can lead to pericardial effusion

Minoxidil Side effects

Hair growth Tachycardia Fluid Retention