Drug Formulations - Chapter 6

Question 1

What is the most common formulation of drug?

Answer 1

Compressed tablet

Question 2

Do different formulations of the same medication cost different prices?

Answer 2

Yes! Different formulations will cost different amounts depending on the price of materials

Question 3

When deciding on a dosage form, what questions should you be asking yourself?

Answer 3

1. Who uses this drug?
2. Is there a reason one dosage form over another is used?

Question 4

What kind of formulation may be best for a patient with schizophrenia?

Answer 4

Long-acting injectable - when having to take medications daily, patients with certain mental disorders (including schizophrenia) may forget to take their medications. Using a long acting injectable formulation may improve overall adhearance.

Question 5

Osmotic Controlled-Release Oral Delivery System MOA

Answer 5

Long-acting formulation that takes water from the gut and is absorbed into the delivery system through osmosis.

Question 6

Long-acting tablets and capsules suffixes

Answer 6

XL
XR
ER
LA
SR
CR
CRT
SA
TR

Question 7

Osmotic Controlled-Release Oral Delivery System Drug Examples

Answer 7

Concerta
Cardura XL
Procardia XL
Delzicol

Question 8

Osmotic Controlled-Release Oral Delivery System counseling point

Answer 8

Possibility of a ghost tablet or capsule in the patient’s stool

Question 9

Two reasons patients might use long acting formualation

Answer 9

Slow release to help reduce side effects
Allow for the drug to be released over time to reduce a peak

Question 10

Big counseling point for long acting medications

Answer 10

Do not crush or chew - dose dumping leading to which could potentially be fatal